restlessness, fatigue, lethargy, disorientation, depressed reflexes, loss
At 8 hours after dose intake, the levels in the milk ranged
large doses of Desmopressin Acetate Nasal Spray with other vasocontrictors may
Nasal Spray in patients with central diabetes insipidus reduces urinary output,
end of the dosing range, reflecting the greater frequency of decreased hepatic,
Desmopressin Acetate Nasal Spray individual dose titration is required because
take, including prescription and over-the-counter medicines, vitamins, and
rabbits by subcutaneous injection from gestation day 6 to 18 during fetal
Desmopressin Acetate Nasal
kidney, and the risk of adverse reactions may be greater in patients with renal
reported voluntarily from a population of uncertain size, it is not always
normal renal function, 4.0 hours in mild renal impairment, 6.6 hours in
Ferring Pharmaceuticals US is voluntarily recalling all lots on the market of DDAVP® Nasal Spray 10 mcg/0.1mL, Desmopressin Acetate Nasal Spray 10 mcg/0.1mL, and STIMATE® Nasal Spray 1.5 … There may be new information. Discard
(See There are reports of an occasional change in response with time, usually greater than 6 months. Avoid use of Desmopressin Acetate Nasal Spray in such patients [see
If administered more than once a day, adjust for an adequate diurnal
The recall involves DDAVP Nasal Spray 10 mcg/0.1mL, Desmopressin Acetate Nasal Spray 10 mcg/0.1mL and Stimate Nasal Spray 1.5 mg/mL. between 4.16 and 101 pg/ml, and the plasma levels ranged between 40 and 242
surgery such as transsphenoidal hypophysectomy) may cause erratic, unreliable
possible to reliably estimate their frequency or establish a causal
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In the US general
Revised: May 2018The following serious reactions are described below and
formulation for the treatment of primary nocturnal enuresis due to a higher
Some patients may show a decreased responsiveness, others a shortened duration of effect. Visit the Copyright © 2020 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment.
thereby increasing water re-absorption in the kidney, and hence reducing urine
older.Desmopressin Acetate Nasal
been approved by the U.S. Food and Drug Administration.You are encouraged to report negative side effects of prescription drugs to the FDA.
and treated, hyponatremia can be fatal.All patients receiving Desmopressin Acetate Nasal Spray
A
reports [seeChronic administration of Desmopressin Acetate Nasal
Visit the Copyright © 2020 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. In addition, in vitro studies with human
bottle with spray pump delivering 50 sprays.Store at Controlled Room Temperature 20 to 25°C (68 to
Nasal Spray is not indicated in pediatric patients less than 4 years of age.Use of Desmopressin Acetate Nasal Spray in pediatric
Desmopressin Acetate Nasal Spray is available as a 5 mL bottle containing an aqueous solution with the spray pump delivering 50 sprays of 10 mcg (0.1 mL) (NDC 66993-025-01). hyponatremia: headache, nausea/vomiting, decreased serum sodium, weight gain,
Use of
Manufactured for: sanofi-aventis U.S. LLC Bridgewater, NJ 08807
recommended human dose based on body surface area (mg/m²).Breastfeeding is not expected to result in clinically
Discard DDAVP Nasal Spray (desmopressin acetate nasal spray) after 50 sprays since the amount delivered thereafter per spray may be substantially less than 10 µg of drug.
intoxication with hyponatremia [see Desmopressin acetate is substantially excreted by the
impairment than patients with normal renal function. use only. intranasal desmopressin is approximately 10 to 40 fold more potent than oral
elsewhere in the labeling:The following adverse reactions have been identified
Possible signs of overdose may include confusion, drowsiness, continuing headache, problems with passing urine and rapid weight gain due to fluid retention.Store at Controlled Room Temperature 20 to 25°C (68 to 77°F) [see USP]. 1.5 fold, 2.4 fold and 3.6 fold higher, respectively compared to that of
with mild, moderate and severe renal impairment, mean desmopressin exposure was
Spray is contraindicated in patients with estimated CLcr by Cockcroft-Gault
patients 4 years of age and older is supported by evidence from adults and pediatric
Fluid intake should be adjusted downward based upon discussion with the physician.Several publications of desmopressin acetate's use in the management of diabetes
re-uptake inhibitors, chlorpromazine, opiate analgesics, NSAIDs, lamotrigine,
and Drug AdministrationRead these instructions before using Desmopressin Acetate
DDAVP spray: Desmopressin nasal solution belongs to 2 classes of medications: antidiuretics and antihemorrhagics.
arginine vasopressin to desmopressin acetate resulted in a decreased