Coreg may have serious side effects that include There are no adequate and well-controlled studies in pregnant or breastfeeding women; Coreg may be used during pregnancy or breastfeeding only if the potential benefit justifies the potential risk to the fetus or infant.Our Coreg Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.This is not a complete list of side effects and others may occur. Carvedilol belongs to a group of medicines called beta-adrenergic blocking agents, beta-blocking agents, or more commonly, beta-blockers. Postmarketing side effects of carvedilol reported include: Blood and lymphatic system : Aplastic anemia Immune system : Hypersensitivity (e.g., severe allergic reactions [ anaphylaxis ], angioedema , hives ) with Coreg and Coreg CR, including cases occurring after initiation of Coreg CR in patients previously treated with Coreg Although there was no overall difference in discontinuation rates, discontinuations were more common in the carvedilol group for postural hypotension (1% versus 0). In a long-term, placebo-controlled trial in severe heart failure, subjects treated with COREG had lower values for hepatic transaminases than subjects treated with placebo, possibly because improvements in cardiac function induced by COREG led to less hepatic COREG has not been associated with clinically significant changes in serum The following adverse reactions have been identified during post-approval use of COREG. DESCRIPTION. Carvedilol is a nonselective β-adrenergic blocking agent with α 1-blocking activity. U.S. placebo-controlled clinical trials, and with severe heart failure enrolled in the COPERNICUS trial. In U.S. controlled clinical trials directly comparing COREG in doses up to 50 mg (n = 1,142) with placebo (n = 462), 4.9% of subjects receiving COREG discontinued for adverse events versus 5.2% of placebo subjects. The only additional adverse events reported in CAPRICORN in greater than 3% of the subjects and more commonly on carvedilol were dyspnea, COREG has been evaluated for safety in hypertension in more than 2,193 subjects in U.S. clinical trials and in 2,976 subjects in international clinical trials. You may report side effects to FDA at 1-800-FDA-1088.This is not a complete list of side effects and others may occur. High blood pressure often has no symptoms. Alcohol may cause the carvedilol in Coreg CR to be released too quickly into the body.If you are being treated for high blood pressure, keep using carvedilol even if you feel well. Call your doctor for medical advice about side effects. Swallow right away without chewing. Call your doctor for medical advice about side effects. Carvedilol is a beta-blocker. Most adverse events reported during therapy with COREG were of mild to moderate severity. In the COMET trial, 1,511 subjects with mild-to-moderate heart failure were treated with COREG for up to 5.9 years (mean: 4.8 years). Follow all directions on your prescription label. Discard the empty capsule.Take carvedilol at the same time every day. The most common side-effects are feeling tired and/or dizzy, and headache. Follow your diet, medication, and exercise routines very closely if you are being treated for hypertension.Store at room temperature away from moisture and heat.Take the missed dose as soon as you remember. These are not all the possible side effects of Coreg. Coreg (carvedilol) is a beta-adrenergic blocking agent (beta-blocker) used to treat heart failure, hypertension, and left ventricular dysfunction after a heart attack. It is important to note that reactions are not really dose-dependent with an exception of bradycardia, abnormal vision, and dizziness. Approximately 36% of the total treated population received COREG for at least 6 months. You should especially avoid drinking alcohol within 2 hours before or after taking extended-release carvedilol (Coreg CR).Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Call your doctor for medical advice about side effects. Beta Blocker Heart Meds Might Pose Special Risks for Women Call your doctor for medical advice about side effects. Do not take this medicine in larger or smaller amounts or for longer than recommended.You may open the carvedilol capsule and sprinkle the medicine into a spoonful of pudding or applesauce to make swallowing easier. SIDE EFFECTS Clinical Trials Experience. Coreg is available in generic form. You should not breast-feed while you are taking carvedilol.Take carvedilol exactly as prescribed by your doctor. Carvedilol side effects. Follow your doctor's instructions.If you are being treated for high blood pressure, keep using this medication even if you feel well. Get up slowly and steady yourself to prevent a fall.Get emergency medical help if you have any of these Call your doctor at once if you have a serious side effect such as:swelling, rapid weight gain, feeling short of breath (even with mild exertion);chest pain, dry cough, wheezing, chest tightness, trouble breathing; orhigh blood sugar (increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, weight loss).This is not a complete list of side effects and others may occur. Stopping suddenly may make your condition worse.Carvedilol can affect your pupils during cataract surgery.