The aim of this study is to characterize the transporter- and enzyme-mediated disposition of glyburide. See the FDA's Safe Disposal of Medicines website (In case of overdose, call the poison control helpline at 1-800-222-1222. Do not take Diabeta, Glynase, or Glynase PresTab if you are allergic to glyburide or any ingredients contained in this drug.Keep out of reach of children. Your doctor will also tell you how to check your response to this medication by measuring your blood sugar levels at home. Glyburide is a CYP2C9 substrate and aprepitant is a CYP2C9 inducer. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.Things to remember when you fill your prescription.WebMD does not provide medical advice, diagnosis or treatment.
Do not take a double dose to make up for a missed one.Glyburide may cause other side effects. Ask your pharmacist any questions you have about refilling your prescription.It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. The information provided here is for informational purposes only. For example, a combination of glyburide with beta blockers, certain decongestants, and oral contraceptives can cause the body to metabolize the medications differently than intended and increase the risk of low blood sugar or make glyburide less effective. Talk to your doctor about the risks of taking glyburide.Keep this medication in the container it came in, tightly closed, and out of reach of children. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Glyburide is not used to treat type 1 diabetes (condition in which the body does not produce insulin and, therefore, cannot control the amount of sugar in the blood) or diabetic ketoacidosis (a serious condition that may occur if high blood sugar is not treated).Over time, people who have diabetes and high blood sugar can develop serious or life-threatening complications, including heart disease, stroke, kidney problems, nerve damage, and eye problems. These tablets come in two forms: regular and micronized. It may be used with other antidiabetic medication. Your doctor and other healthcare providers will talk to you about the best way to manage your diabetes.Glyburide comes as a tablet to take by mouth. GLYBURIDE/BOSENTAN; Serious Interactions. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. Glyburide is in a class of medications called sulfonylureas. It is also important information to carry with you in case of emergencies.URL of this page: https://medlineplus.gov/druginfo/meds/a684058.htmlTo use the sharing features on this page, please enable JavaScript. In case of overdose, get medical help or contact a Copyright © 2020 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. Glyburide lowers blood sugar by causing the pancreas to produce insulin (a natural substance that is needed to break down sugar in the body) and helping the body use insulin effic… Never use this combination of drugs because of high risk for dangerous interactionPotential for serious interaction; regular monitoring by your doctor required or alternate medication may be neededPotential for significant interaction (monitoring by your doctor is likely required)Copyright © 2020 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. It is usually taken once a day with breakfast or the first main meal of the day. Rebetol (Ribavirin) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources.
Semi-mechanistic or extended PBPK modeling of glyburide was reported recently to predict certain drug interactions or drug disposition in pregnancy (26,27). Administration of a CYP2C9 substrate, tolbutamide, on days 1, 4, 8, and 15 with a 3-day regimen of oral aprepitant (125 mg/80 mg/80 mg) decreased the tolbutamide AUC by 23% on day 4, 28% on day 8, and … Drug Metab Pharmacokinet. Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them.
Follow these instructions carefully.You should always wear a diabetic identification bracelet to be sure you get proper treatment in an emergency.Do not let anyone else take your medication. Before taking glyburide, tell your doctor if you are allergic to sulfa drugs, if you have been using insulin or chlorpropamide (Diabinese), or if you have hemolytic anemia (a lack of red blood cells), an enzyme deficiency (G6PD), a nerve disorder, liver disease, or kidney disease. Drug-drug interactions are a particularly important type of adverse drug event because they are often predictable based on previous reports, clinical studies, and an understanding of pharmacologic principles. An interaction is when a substance changes the way a drug works.