Brigatinib may enhance the bradycardic effect of Antihypertensive Agents.Brimonidine (Topical): May enhance the hypotensive effect of Blood Pressure Lowering Agents.Bromperidol: May diminish the hypotensive effect of Blood Pressure Lowering Agents. Cardiac Glycosides: Telmisartan may increase the serum concentration of Cardiac Glycosides. Hydrochlorothiazide: Inhibits sodium reabsorption in the distal tubules causing increased excretion of sodium and water as well as potassium and hydrogen ionsHypersensitivity to telmisartan, hydrochlorothiazide, or any component of the formulation; concomitant use with aliskiren in patients with diabetes mellitus; anuria.Documentation of allergenic cross-reactivity for angiotensin II receptor blockers and thiazide-related diuretics is limited.
Systolic and diastolic are the two readings in which blood pressure is Treatment of heart disease involves control of heart disease risk factors through lifestyle changes, medications, and/or stenting or bypass surgery. Dofetilide: HydroCHLOROthiazide may enhance the QTc-prolonging effect of Dofetilide. Hydrochlorothiazide / telmisartan systemic 12.5 mg / 40 mg (TH1M) Monitor for increased lithium therapeutic/toxic effects if a thiazide is initiated/dose increased, or decreased effects if a thiazide is discontinued/dose decreased.Lithium: Angiotensin II Receptor Blockers may increase the serum concentration of Lithium. There is a potential for cross-reactivity between members of a specific class (eg, two antibiotic sulfonamides). Aminolevulinic Acid (Topical): Photosensitizing Agents may enhance the photosensitizing effect of Aminolevulinic Acid (Topical). shaking,
Consider alternatives when possible. Specifically, the risk of acute phosphate nephropathy may be enhanced. Additional treatments may be needed if uncontrolled intraocular pressure persists. Verteporfin: Photosensitizing Agents may enhance the photosensitizing effect of Verteporfin. Side effects, dosing information, drug interactions, and warnings and precautions should be reviewed prior to taking any medication.What causes high blood pressure (hypertension)? If combined, mecamylamine prescribing information suggests reducing the mecamylamine dose by 50% in order to avoid excessive hypotension.Methenamine: Thiazide and Thiazide-Like Diuretics may diminish the therapeutic effect of Methenamine. Levodopa-Containing Products: Blood Pressure Lowering Agents may enhance the hypotensive effect of Levodopa-Containing Products. Management: Condsider reducing the lithium dose by 50% upon initiation of a thiazide diuretic.
Yohimbine: May diminish the antihypertensive effect of Antihypertensive Agents.Central nervous system: Dizziness (5%), fatigue (3%)Gastrointestinal: Diarrhea (3%), nausea (2%), abdominal pain (<2%), dyspepsia (<2%), vomiting (<2%)Renal: Increased blood urea nitrogen (3%), increased serum creatinine (1%)Respiratory: Upper respiratory tract infection (8%), sinusitis (4%), flu-like symptoms (2%), bronchitis (<2%), pharyngitis (<2%)<1%, postmarketing, and/or case reports: Anaphylaxis, angioedema, atrial fibrillation, bradycardia, cardiac failure, cough, edema, eosinophilia, erectile dysfunction, headache, hepatic disease, hepatic insufficiency, hypoglycemia (in diabetic patients), increased creatine phosphokinase, myocardial infarction, orthostatic hypotension, renal failure (including acute renal failure), renal insufficiency, rhabdomyolysis, skin rash (including toxicoderma, urticaria), syncope, tachycardia, tendon pain (including tendonitis, tenosynovitis), urinary tract infection, vertigo, weaknessDrugs that act directly on the renin-angiotensin system can cause injury and death to the developing fetus.