See manufacturer's labeling.• Propylene glycol: Some dosage forms may contain propylene glycol; large amounts are potentially toxic and have been associated with hyperosmolality, lactic acidosis, seizures, and respiratory depression; use caution (AAP 1997; Zar 2007). Screening is recommended.• Prostatic hyperplasia/urinary stricture: Use with caution in patients with prostatic hyperplasia and/or urinary stricture.• Respiratory disease: Use with caution in patients with asthma or chronic obstructive pulmonary disease (COPD).• Drug-drug interactions: Potentially significant interactions may exist, requiring dose or frequency adjustment, additional monitoring, and/or selection of alternative therapy. Aclidinium: May enhance the anticholinergic effect of Anticholinergic Agents.Alcohol (Ethyl): CNS Depressants may enhance the CNS depressant effect of Alcohol (Ethyl). Segidrin, Sehydrin, Sulfate d'Hydrazine, Sulfato de Hidracina.Hydrazine sulfate contains a chemical that affects the body. Management: Use caution if coadministering blonanserin and CNS depressants; dose reduction of the other CNS depressant may be required. Glycopyrrolate (Oral Inhalation): Anticholinergic Agents may enhance the anticholinergic effect of Glycopyrrolate (Oral Inhalation). Management: Monitor closely for evidence of excessive CNS depression. Rotigotine: CNS Depressants may enhance the sedative effect of Rotigotine. Management: Patients taking perampanel with any other drug that has CNS depressant activities should avoid complex and high-risk activities, particularly those such as driving that require alertness and coordination, until they have experience using the combination.Piribedil: CNS Depressants may enhance the CNS depressant effect of Piribedil. Oral hydroxyzine is contraindicated in patients with a prolonged QT interval.• Glaucoma: Use with caution in patients with narrow-angle glaucoma; condition may be exacerbated by cholinergic blockade. Levosalbutamol / Levalbuterol is a bronchodilator while Ipratropium is an anticholinergic. Possible withdrawal symptoms have been observed in neonates following chronic maternal use of hydroxyzine during pregnancy (Prenner 1977; Serreau 2005).Hydroxyzine is approved for pre- and postpartum adjunctive therapy to control emesis, reduce opioid dosage, and treat anxiety. The body breaks isoniazid down to hydrazine. Topiramate: Anticholinergic Agents may enhance the adverse/toxic effect of Topiramate. Protect from light; do not freeze.Acetylcholinesterase Inhibitors: Anticholinergic Agents may diminish the therapeutic effect of Acetylcholinesterase Inhibitors. Management: Drugs listed as exceptions to this monograph are discussed in further detail in separate drug interaction monographs.Magnesium Sulfate: May enhance the CNS depressant effect of CNS Depressants.Meperidine: HydrOXYzine may enhance the CNS depressant effect of Meperidine.
Get up to 20% on Prescription Medications only at our Pharmacy. If combined, limit the dosages and duration of each drug.Orphenadrine: CNS Depressants may enhance the CNS depressant effect of Orphenadrine. They work by relaxing the muscles in the airways and widen the airways. Rufinamide: May enhance the adverse/toxic effect of CNS Depressants. How Combimist-L Inhaler worksCombimist-L 50mcg/20mcg Inhaler is a combination of two medicines: Levosalbutamol / Levalbuterol and Ipratropium.
Pitolisant: Antihistamines may diminish the therapeutic effect of Pitolisant. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Protect from light.Suspension, syrup, tablets: Store at 20°C to 25°C (68°F to 77°F). Dimethindene (Topical): May enhance the CNS depressant effect of CNS Depressants.Doxylamine: May enhance the CNS depressant effect of CNS Depressants. Hydroxyzine crosses the placenta. Taking hydrazine sulfate along with sedative medications might cause too much sleepiness.Isoniazid is a drug used for tuberculosis. Select one or more newsletters to continue. Using both isoniazid and hydrazine might increase the risk of liver damage.Hydrazine sulfate might decrease blood sugar. Pramlintide: May enhance the anticholinergic effect of Anticholinergic Agents.