: Effectiveness and pharmacokinetics of indomethacin in premature newborns with patient ductus arteriosus.

2019 May;98(20):e15742. : Plasma indomethacin levels in preterm newborn infants with symptomatic patient ductus arteriosus — clinical and echocardiographic assessments of response. : Comparative bioavailability: Influence of various diets on the bioavailability of indomethacin. Journal of Obstetrics and Gynecology 44: 787–792 (1974).Department of Physical Medicine T2002, Rigshospitalet, University Hospital, 18 Tagenovej, DK-2200, Copenhagen, DenmarkYou can also search for this author in

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Plasma concentrations of indomethacin have been studied in 5 healthy volunteers after single and multiple doses (25 mg intravenously [iv], 25, 50, and 100 mg orally, 100 mg rectally, and 25 mg three times daily [tid]. Ductal closure in utero by a prostaglandin synthetase inhibitor. : Pharmacokinetics of indomethazine and metabolites of indomethazine continuously applied in patients with healthy and damaged kidneys. The half-life of the beta-phase varied between 2.6 and 11.2 hr. 1. and Kwan, K.C. Journal of Pharmacokinetics and Biopharmaceutics 4: 255–280 (1975).Lindquist, B.; Jensen, K.M. : Prostaglandins as mediators of hypercalcemia associated with certain types of cancer. ; Windholz, T.B. ; Buchannan, W.W. and Rhymer, A.R. and Jansen, J.A. Indomethacin (l-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid) is an anti-inflammatory antipyretic drug commonly used for symptomatic relief of pain and stiffness in rheumatic diseases. 2014 May-Jun;28(3):793-8. doi: 10.1111/jvim.12345. ; Famaey, J.P. and Dick, W.C.: The clinical significance of the indomethacin-probenecid interaction. ; Van Den Heuvel, W.J.A. ; Hooke, K.F. ; Baty, J.D.

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and Steen, B.: Convulsions in a breast-fed infant after maternal indomethacin. Clinical Pharmacology and Therapeutics 15: 247–252 (1974).Lockie, L.M. ; Baber, N.; Chan, K. and Orme, M.: Quantitative gas-liquid Chromatographic method for the determination of indomethacin in biological fluids. A double-blind study utilizing indomethacin plasma levels.

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; Simkin, P.A. : Interaction of indomethacin and acetylsalicylic acid as shown by the serum concentrations of indomethacin and salicylate.