Your doctor may occasionally change your dose. Avoid tanning booths and sunlamps. These side effects may go away during treatment as your body adjusts to the medicine. Geriatric patients are more sensitive to the side effects of antipsychotics, including prochlorperazine. If your dose is different, do not change it unless your doctor tells you to do so.The amount of medicine that you take depends on the strength of the medicine. Prochlorperazine is a synthetic propylpiperazine derivative of phenothiazine with antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Should it be necessary to reinstitute treatment or increase the dosage of the agent or switch to a different antipsychotic agent, the syndrome may be masked.It has been reported that fine vermicular movements of the tongue may be an early sign of the syndrome, and if the medication is stopped at that time, the syndrome may not develop.Avoid getting the injection solution on hands or clothing because of the possibility of contact dermatitis.Adverse reactions with different phenothiazines vary in type, frequency, and the mechanism of occurrence, i.e., some are dose-related, while others involve individual patient sensitivity.Some adverse reactions may be more likely to occur, or occur with greater intensity, in patients with special medical problems, e.g., patients with mitral insufficiency or pheochromocytoma have experienced severe hypotension following recommended doses of certain phenothiazines.Not all of the following adverse reactions have been observed with every phenothiazine derivative but they have been reported with one or more and should be borne in mind when drugs of this class are administered: extrapyramidal symptoms (opisthotonos, oculogyric crisis, hyper-reflexia, dystonias, akathisia, dyskinesia, parkinsonism), some of which have lasted months and even years, particularly in elderly patients with previous brain damage; grand mal and petit mal convulsions, particularly in patients with EEG abnormalities or history of such disorders; altered cerebrospinal fluid proteins; cerebral edema; intensification and prolongation of the action of central nervous system depressants (opiates, analgesics, antihistamines, barbiturates, alcohol), atropine, heat, organophosphorus insecticides; autonomic reactions (dryness of mouth, nasal congestion, headache, nausea, constipation, obstipation, adynamic ileus, ejaculatory disorders/impotence, priapism, atonic colon, urinary retention, miosis and mydriasis); reactivation of psychotic processes, catatonic-like states; hypotension (sometimes fatal); cardiac arrest; blood dyscrasias (pancytopenia, thrombocytopenic purpura, leukopenia, agranulocytosis, eosinophilia, hemolytic anemia, aplastic anemia); liver damage (jaundice, biliary stasis); endocrine disturbances (hyperglycemia, hypoglycemia, glycosuria, lactation, galactorrhea, gynecomastia, menstrual irregularities, false-positive pregnancy tests); skin disorders (photosensitivity, itching, erythema, urticaria, eczema up to exfoliative dermatitis); other allergic reactions (asthma, laryngeal edema, angioneurotic edema, anaphylactoid reactions); peripheral edema; reversed epinephrine effect; hyperpyrexia; mild fever after large IM doses; increased appetite; increased weight; a systemic lupus erythematosus-like syndrome; pigmentary retinopathy; with prolonged administration of substantial doses, skin pigmentation, epithelial keratopathy, and lenticular and corneal deposits.EKG changes-particularly nonspecific, usually reversible Q- and T-wave distortions-have been observed in some patients receiving phenothiazines.Although phenothiazines cause neither psychic nor physical dependence, sudden discontinuation in long-term psychiatric patients may cause temporary symptoms, e.g., nausea and vomiting, dizziness, tremulousness.Primarily involvement of the extrapyramidal mechanism producing some of the dystonic reactions described above. There have been a few observations of fatty changes in the livers of patients who have died while receiving the drug. Treatment with antiparkinsonian agents, benzodiazepines or propranolol may be helpful.Symptoms may include mask-like faces, drooling, tremors, pillrolling motion, cogwheel rigidity, and shuffling gait. Prochlorperazine is used to treat nervous, emotional, and mental conditions (eg, schizophrenia) and non-psychotic anxiety. The syndrome can also develop, although much less frequently, after relatively brief treatment periods at low doses. Use the medicine exactly as directed.Prochlorperazine doses are based on weight in children. It is a less preferred medication for anxiety. This syndrome appears in all age groups. Subsequent doses may be given by the same route if necessary.Calculate each dose on the basis of 0.06 mg of the drug per For ages under 12, calculate each dose on the basis of 0.06 mg of prochlorperazine per Control is usually obtained with one dose. If therapy is reinstituted, it should be at a lower dosage. You may report side effects to FDA at 1-800-FDA-1088.Tell your doctor about all your current medicines. Generally, therapy of a few weeks to two or three months will suffice. Benicar usados benicarlo spain parador Sildenafil (Viagra®), candid v gel price in india dog-cheap by a different mechanism, also opens up the blood vessels in the lung and may be a useful treatment for HAPE.! Each mL contains prochlorperazine 5 mg as the edisylate, monobasic sodium phosphate monohydrate 5 mg, sodium tartrate dihydrate 12 mg, saccharin sodium 0.9 mg and benzyl alcohol 7.5 mg in Water for Injection.
Patients with a preexisting low WBC or a history of drug induced leukopenia/neutropenia should have their complete blood count (CBC) monitored frequently during the first few months of therapy and should discontinue Prochlorperazine Edisylate Injection USP at the first sign of a decline in WBC in the absence of other causative factors.Patients with neutropenia should be carefully monitored for fever or other symptoms or signs of infection and treated promptly if such symptoms or signs occur. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. Dosage and frequency of administration should be adjusted according to the severity of the symptoms and the response of the patient.