range for thioridazine begins at 1 mg/dL, and 2 to 8 mg/dL is the An airway must be established and maintained. But if breathing has been depressed for a long period before treatment, brain injury may occur. Pharmacokinetics: fail to respond adequately to treatment with other However, the prescriber should be aware that thioridazine has not been systematically evaluated in controlled trials in treatment Since thioridazine is associated with a dose-related prolongation of the QTc
It is usually taken two to four times a day. Once effective control of symptoms has been achieved, the dosage may be reduced gradually to determine the minimum maintenance dose. The hands should then be used to gently rub the gel into the skin. drugs and other drugs not essential to concurrent therapy, 2) intensive symptomatic
interval, which is a potentially life-threatening event, its use should be reserved
The longer you take thioridazine, the more likely you are to develop this movement disorder. Thioridazine has little antiemetic activity. Thioridazine is available as tablets of 10, 25, 50 and 100 mg in generic forms and previously under the brand name Mellaril. defect leading to reduced levels of activity of P450 2D6 (see The basic pharmacological activity of thioridazine is similar to that of other phenothiazines, but is associated with minimal extrapyramidal stimulation.However, thioridazine has been shown to prolong the QTc interval in a dose-dependent
There are several published case reports of torsade de pointes and sudden death associated with thioridazine treatment. Adequate In managing overdosage, the physician should always consider the possibility
We comply with the HONcode standard for trustworthy health information - The dosing card should be used for each application of drug product.
the risk of serious, potentially fatal, cardiac arrhythmias, such as torsade
under Effects and clinical complications of acute overdose involving phenothiazines may include:Toxic dose and blood concentration ranges for the phenothiazines have not been
would produce additive prolongation of the QTc interval and, thus, such use
However, generic versions are still available in the US. Many medicines should not be taken together with thioridazine because they may cause this heart rhythm disorder or other serious medical problems. Once your symptoms have been controlled for some time, your doctor may decrease your dose. (e.g., fluoxetine and paroxetine), and certain other drugs (e.g., fluvoxamine,
The 2 g … After observing the response to initial therapy with Voltaren, the dose and frequency should be adjusted to suit an individual patient’s needs. The risk of this side effect is higher in women and older adults.Tell your doctor if you are pregnant or plan to become pregnant while using thioridazine.Taking antipsychotic medication during the last 3 months of pregnancy may cause problems in the newborn, such as withdrawal symptoms, breathing problems, feeding problems, fussiness, tremors, and limp or stiff muscles. The entire hand includes the palm, back of the hands, and the fingers. There are other medications that can be used to treat your condition that are less likely to cause this life-threatening side effect. reported.As in the case of other phenothiazines, thioridazine is capable of potentiating central nervous system depressants (e.g., alcohol, anesthetics, barbiturates, narcotics, opiates, other psychoactive drugs, etc.) propranolol, and pindolol) appear to appreciably inhibit the metabolism of thioridazine. should not be co-administered.There are no studies of the co-administration of thioridazine and other drugs
Do not apply more than 8 g daily to any single joint of the upper extremities.Total dose should not exceed 32 g per day, over all affected joints.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. with M58 on one side and 25 on the other side. with M61 on one side and 100 on the other side. Attention should be paid to the fact that phenothiazines are capable of potentiating A potentially fatal symptom complex sometimes referred to as Neuroleptic Malignant
Information is also available online at Below are symptoms of an overdose of thioridazine in different parts of the body.Take the container with you to the hospital, if possible.Your doctor will measure and monitor the person’s vital signs, including temperature, pulse, breathing rate, and blood pressure.