Because cross-reactivity between aspirin and other NSAIDs has been reported in such aspirin-sensitive patients, CELEBREX is contraindicated in patients with this form of aspirin sensitivity [Serious skin reactions have occurred following treatment with CELEBREX, including erythema multiforme, exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), toxic epidermal necrolysis (TEN), drug reaction with eosinophilia and systemic symptoms (DRESS), and acute generalized exanthematous pustulosis (AGEP). On following days, the typical dosage … Forced diuresis, alkalinization of urine, hemodialysis, or hemoperfusion may not be useful due to high protein binding.For additional information about overdosage treatment contact a poison control center (1-800-222-1222).CELEBREX (celecoxib) capsule is a nonsteroidal anti-inflammatory drug, available as capsules containing 50 mg, 100 mg, 200 mg and 400 mg celecoxib for oral administration.
Inform patients, families, or their caregivers of the following information before initiating therapy with CELEBREX and periodically during the course of ongoing therapy. Its molecular formula is CCelecoxib is a white to off-white powder with a pKa of 11.1 (sulfonamide moiety). CELEBREX PATIENTS WITH, OR AT HIGH RISK FOR, CARDIOVASCULAR DISEASE TAKING CELEBREX 100-200 MG 2 TIMES A DAY. Since celecoxib is an inhibitor of prostaglandin synthesis, its mode of action may be due to a decrease of prostaglandins in peripheral tissues.In clinical trials using normal volunteers, CELEBREX at single doses up to 800 mg and multiple doses of 600 mg twice daily for up to 7 days duration (higher than recommended therapeutic doses) had no effect on reduction of platelet aggregation or increase in bleeding time. The inactive ingredients in CELEBREX include: croscarmellose sodium, edible inks, gelatin, lactose monohydrate, magnesium stearate, povidone and sodium lauryl sulfate.Celecoxib has analgesic, anti-inflammatory, and antipyretic properties.The mechanism of action of CELEBREX is believed to be due to inhibition of prostaglandin synthesis, primarily via inhibition of COX-2.Celecoxib is a potent inhibitor of prostaglandin synthesis in vitro. Citalopram is an antidepressant medication that affects neurotransmitters, the chemicals that nerves within the brain use to communicate with each other. 0025-1530-02 The calculated average daily infant dose was 10 to 40 mcg/kg/day, less than 1% of the weight-based therapeutic dose for a two-year old-child. Updated 5:03 PM ET, Sun November 13, 2016 . Physicians and patients should remain alert for the development of such events, throughout the entire treatment course, even in the absence of previous CV symptoms. Patients on long-term treatment with CELEBREX should have their hemoglobin or hematocrit checked if they exhibit any signs or symptoms of anemia or blood loss.NSAIDs, including CELEBREX, may increase the risk of bleeding events. For current full prescribing information, please visit www.pfizer.com.For patient information, please call 1-800-249-2692For patient information, please call 1-800-249-2692Copy the URL below and paste it into your RSS Reader application.
Due to inconsistencies between the drug labels on DailyMed and the pill images provided by Adult dosage (ages 18 years and older) The typical dosage is 400 mg for the first dose followed by a 200-mg dose about 8–12 hours later if needed. You may be more sensitive to sunlight if you take celecoxib. Use the lowest effective dosage for the shortest duration consistent with individual patient treatment goals [These doses can be given without regard to timing of meals.For OA, the dosage is 200 mg per day administered as a single dose or as 100 mg twice daily.For RA, the dosage is 100 mg to 200 mg twice daily.For JRA, the dosage for pediatric patients (age 2 years and older) is based on weight.