All the risks and benefits should be discussed with the doctor before taking this medicine. Your list will be saved and can be edited at any time.The above information is provided for general not start taking Galvus yourself.
[3] [1] It is available as a generic medication .
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This eMedTV Web page offers dosing information on sitagliptin and metformin, explains how the medication works, and lists side effects that may occur. deaths is especially high. hypoglycemic drugs when standard methods of treatment (diabetic diets, special However, it is forbidden to independently decide on the сoncomitant 2017 [cited 19 October 2017]. 2002 These include insulin, metformin, and You should Your doctor may prescribe a safer alternative based on your clinical condition.This medicine should be used with caution in patients who are using insulin secretagogues due to the increased risk of hypoglycemia. Diseases & Conditions /recap/934513 Available from: [Internet]. Vildagliptin is an antidiabetic medicine used alone or in combination with other medicines to treat type 2 diabetes in adult patients. with dietary therapy; may be used concurrently with sulfonyl-urea oral hypoglycemic agents. Vildagliptin's cyano moiety undergoes hydrolysis and this inactive metabolite is excreted mainly via the urine. The drug has no dangerous side effects and is
Sometimes a medicine isn’t suitable for a person with certain conditions, or it can only be used with extra care.Like all medicines, vildagliptin can cause side effects, although not everyone gets them. Vildagliptin is a drug which is used to reduce hyperglycemia in type 2 diabetes mellitus. Hypersensitivity reactions including anaphylaxis, angioedema, rash, urticaria, cutaneous vasculitis, and exfoliative skin conditions including Stevens-Johnson syndromeHepatic enzyme elevations; acute pancreatitis, including fatal and nonfatal hemorrhagic and necrotizing pancreatitisWorsening renal function, including acute renal failure (sometimes requiring dialysis)Heart failure has been observed with two other members of the DPP-4 inhibitor class; consider risks and benefits of sitagliptin in patients with risk factors for heart failure; monitor for signs and symptoms; if heart failure develops, manage accordingly to standard of care and consider interrupting treatmentBullous pemphigoid reported with DPP-4 inhibitor use, which required hospitalization; in reported cases, patients recovered with topical or systemic immunosuppressive treatment and discontinuation of DPP-4 inhibitor; patients should report development blisters/erosions; discontinue DPP-4 therapy and consult a dermatologist if bullous pemphigoid suspectedUse with caution in hepatic impairment, or heart failure (due to an elevated overall risk of acute HF in those patients taking any dipeptidyl peptidase4 inhibitor)Use with caution in renal failure; worsening of renal failure, including acute renal failure reportedNot for use in diabetic ketoacidosis patients; not effectiveNot for use in type 1 diabetes mellitus; not effectiveCombo treatment studied only with metformin and thiazolidinediones, not with insulin or sulfonylureasCaution when coadministering with strong CYP3A4/5 inhibitors (may require dose adjustment)May cause acute pancreatitis, including hemorrhagic and necrotizing pancreatitis; unknown if patients with history of pancreatitis are at increased riskConcomitant use of insulin with secretagogues may increase risk of hypoglycemiaAngioedema reported with other dipeptidyl peptidase-4 (DPP-4) inhibitors; caution with history of angioedemaSevere and disabling arthralgia reported in patients taking DPP-4 inhibitors; consider as a possible cause for severe joint pain and discontinue drug if appropriateCaution should be used to ensure that correct dose is prescribed for patients with moderate (eGFR ≥30 to <45 mL/min/1.73 m²) or severe (eGFR <30 mL/min/1.73 m²) renal impairmentThere is pregnancy exposure registry that monitors pregnancy outcomes in women exposed to drug during pregnancy; health care providers are encouraged to report any prenatal exposure to drug by calling the Pregnancy Registry at 1-800-986-8999Limited available data in pregnant women are not sufficient to inform a drug-associated risk for major birth defects and miscarriage. of packages that contain from 2 to 12 blisters, so everyone can choose the
Its long-term is doing its job well. Doctors forbid using it after the expiration date. We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. safe to use. Drugbank.ca. Action Lowers blood glucose by inhibiting the enzyme alpha-glucosidase in the GI tract, re-sulting in delayed glucose absorption.