School Baroda Medical College; Course Title MEDICINE NOTES; Uploaded By PayToKiran; Pages 50 Ratings 100% (1) 1 out of 1 people found this document helpful; This preview shows page 23 - 26 out of 50 pages. 3 CONTINUED zidovudine PDFPage#3 dexrazoxane. Lancet 357 (2001): 592-837. Montastruc G, Favreliere S, Sommet A, et al. Int Conf AIDS 9 (1993): 46545. 8. More rarely, it can cause anemia and low white blood cell counts. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects.
CAPITALS indicate life-threatening, underlines indicate most frequent. Patient/FamilyTeaching Instruct patient to take zidovudine as directed, around the clock, even if … When zidovudine is used to treat HIV infection, the medicine is always used in combination with other HIV medicines. If you miss a dose, take it as soon as possible and continue with your regular schedule. Merenich JA, Hannon RN, Gentry RH, Harrison SM "Azidothymidine-induced hyperpigmentation mimicking primary adrenal insufficiency." Dubin G, Braffman MN "Zidovudine-induced hepatotoxicity." Keep all Do not flush medications down the toilet or pour them into a drain unless instructed to do so. JAMA 296 (2006): 827-4316. Piacenti FJ "An update and review of antiretroviral therapy." Ann Intern Med 110 (1989): 85-640. Moore RD, Creagh-Kirk T, Keruly J, et al "Long-term safety and efficacy of zidovudine in patients with advanced human immunodefiency virus disease." You may report side effects to Health Canada at 1-866-234-2345.Liquid products may contain sugar. Am J Med 93 (1992): 94-643. These lists are not exhaustive.AZT should never be combined with d4T (Zerit, stavudine), as these drugs interfere with each other.The following drugs can affect the bone marrow, decreasing the production of white and/or red blood cells. Strikethrough Discontinued. If it is near the time of the next dose, skip the missed dose. Arnaudo E, Dalakas M, Shanske S, et al "Depletion of muscle mitochondrial DNA in AIDS patients with zidovudine-induced myopathy." RETROVIR Capsules, Zidovudine 100 mg: AUST R 178834 (bottle), AUST R 178383 (blister) RETROVIR Capsules, Zidovudine 250 mg: AUST R 178384 RETROVIR Syrup, Zidovudine 50 mg/5mL: AUST R 41043.
The most common side effects of AZT can include headache, nausea, and loss of appetite. The most common side effects of AZT can include headache, nausea, and loss of appetite. South Med J 92 (1999): 421-344. "Anti-HIV agents. During labour and delivery, zidovudine is given intravenously by the hospital until the baby is born. Slayter KL, Pierce SM, Marrie TJ "Possible zidovudine-associated hypersensitivity." Using AZT with these or other drugs that affect the bone marrow can increase the risk of infections and/or anemia:AZT should be used cautiously with these drugs, or not at all.For some people, but not all, methadone increases the blood level of AZT. Till M, Kochvar G, Murphy R, Phair J "Myopathy associated with zidovudine use in HIV-1 infection." For more information on ART, see CATIE's For many people with HIV, the use of ART has increased their CD4+ cell counts and decreased the amount of HIV in their blood (viral load). When zidovudine is used to treat HIV infection, the medicine is always used … AZT is usually taken as a component of Combivir and Trizivir, which are single tablets containing AZT plus one or more other anti-HIV drugs.To explain how AZT works, we need to first tell you some information about HIV. AAPS PharmSciTech. In vivo antagonism with zidovudine plus stavudine combination therapy. CAPITALS indicate life-threatening, underlines indicate most frequent. Wright JM, Sachdev PS, Perkins RJ, Rodriguez P "Zidovudine-related mania."
J Antimicrob Chemother 58 (2006): 637-4425. Gradon JD, Chapnick EK, Sepkowitz DV "Zidovudine-induced hepatitis." All medications should always be taken as prescribed and directed.Retrovir is licensed in Canada for the treatment of HIV infection in adults, in combination with other anti-HIV drugs. Ann Intern Med 112 (1990): 65-635. Some features of the lipodystrophy syndrome include:Together with these physical changes, lab tests of your blood may detect the following:The precise causes of the HIV lipodystrophy syndrome are not clear and are difficult to understand because in some people with HIV there may be one or more aspects of the syndrome taking place. Fellay J, Boubaker K, Ledergerber B, et al. Arch Intern Med 162 (2002): 355-661. Dose reduction has not affected the course of myopathy, although drug discontinuation sometimes resulted in improvement of symptoms, generally within a month.
"Exploratory study comparing the metabolic toxicities of a lopinavir/ritonavir plus saquinavir dual protease inhibitor regimen versus a lopinavir/ritonavir plus zidovudine/lamivudine nucleoside regimen." Dalakas MC, Illa I, Pezeshkpour GH, et al "Mitochondrial myopathy caused by long-term zidovudine therapy." Antoniou T, Gough K, Yoong D and Arbess G. Severe anemia secondary to a probable drug interaction between zidovudine and valproic acid. Pharmacotherapy 16 (1996): 79-8160. To decrease your risk of spreading HIV disease to others, do all of the following: (1) continue to take all HIV medications exactly as prescribed by your doctor, (2) always use an effective barrier method (latex or polyurethane The dosage is based on your medical condition and response to treatment.