Your doctor will write the number of refills authorized on your prescription.Your doctor may do certain tests during your treatment with this drug.
Cerner Multum, Inc. "Australian Product Information." Hepatotoxicity is often manifest as cholestasis and/or acute focal hepatocellular necrosis, and is generally reversible following discontinuation of azathioprine therapy. I startedon Prednisolone and was then put on Imuran. Responses (1) IN. El-Azhary RA, Brunner KL, Gibson LE "Sweet syndrome as a manifestation of azathioprine hypersensitivity." HermannsLe T, Pierard GE "Azathioprine-induced skin peeling syndrome."
While that has a positive effect on mood, it also can affect appetite. J R Soc Med 79 (1986): 171-361. SSRIs work by blocking a receptor in the brain that reabsorbs serotonin, which makes more of this “feel-good” chemical available to send messages between nerve cells. Eland IA, van Puijenbroek EP, Sturkenboom MJ, Wilson JH, Stricker BH "Drug-associated acute pancreatitis: twenty-one years of spontaneous reporting in The Netherlands."
Ruxolitinib can cause weight gain by blocking leptin signaling in the brain via JAK2/STAT3 Hematologic toxicities and neoplasia were reported more often in renal homograft recipients than in patients using azathioprine for Bone marrow suppression is dose related and is the most common cause for dosage reductions. J Hepatol 23 (1995): 351-489. Risk of secondary infection and malignancy is also significant. Black, tarry stools 2. bleeding gums 3. blood in the urine or stools 4. chest pain 5. chills 6. cough 7. fever 8. hoarseness 9. lower back or side pain 10. painful or difficult urination 11. pinpoint red spots on the skin 12. sore throat 13. sores, ulcers, or white spots on the lips or in the mouth 14. swollen glands 15. unusual bleeding or bruising 16. unusual tiredness or weakness
Transplantation 68 (1999): 976-8060. Cooper C, Minihane N, Cotton DW, Cawley MI "Azathioprine hypersensitivity manifesting as acute focal hepatocellular necrosis."
Healthline Media does not provide medical advice, diagnosis, or treatment. Brown G, Boldt C, Webb JG, Halperin L "Azathioprine-induced multisystem organ failure and cardiogenic shock." Pandhi RK, Gupta LK, Girdhar M "Azathioprine-induced drug fever."
Ann Rheum Dis 47 (1988): 988-9242.
Available from: URL: http://www.tga.gov.au/adr/aadrb/aadr0612.htm." Eur J Clin Pharmacol 63 (2007): 875-885.
Transplantation 41 (1986): 55-955. It’s important to note that drugs in these medication families are associated with weight gain as a side effect, but not all drugs in a given medication family will cause weight gain. Duttera MJ, Carolla RL, Gallelli JF, et al "Hematuria and crystalluria after high-dose 6-mercaptopurine administration." Patel AA, Swerlick RA, McCall CO "Azathioprine in dermatology: the past, the present, and the future." Arthritis Rheum 38 (1995): 142-515. Ann Rheum Dis 47 (1988): 503-59. Tage-Jensen U, Schlichting P, Thomsen HF, et al "Malignancies following long-term azathioprine treatment in chronic liver disease." To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.Examples of drugs that can cause interactions with azathioprine are listed below.These are TNF-modifier drugs.
Gerlag PG, van Hooff JP "Hepatic sinusoidal dilatation with portal hypertension during azathioprine treatment: a cause of chronic liver disease after kidney transplantation." Weight Gain is #3 concern in Imuran discussions.
Larvol L, Soule JC, Letourneau A "Reversible lymphoma in the setting of azathioprine therapy for Crohn's disease." Pharmacotherapy 17 (1997): 815-884.