Sereflo is indicated for use in adults with asthma 18 years of age and older only. SEROFLO INHALER is contraindicated in patients with a history of hypersensitivity to … Co-administration with erythromycin was not associated with any serious adverse effects.There are no data in humans. Treatment was stepped up every 12 weeks until **total control was achieved or the highest dose of study drug was reached. There are no data available for use of salmeterol and fluticasone propionate in patients with hepatic impairment.Patients should be instructed in the proper use of their inhaler (see patient information leaflet) During inhalation, the patient should preferably sit or stand. Pressurized metered dose inhalers (pMDIs), first introduced in 1956, are considered an effective delivery method for many important drugs used to treat asthma and chronic obstructive pulmonary disease (COPD). It is also thought to inhibit cytosolic phospholipase A2, which controls the biosynthesis of potent inflammation mediators like prostaglandins and leukotrienes, thereby reducing inflammation.Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.Drugs like Atazanavir, Amprenavir, Itraconazole, Mifepristone, Carvedilol, Clarithromycin, Labetalol interact with Seroflo 250 Inhaler.Seroflo 250 Inhaler is not prescribed to patients with We don't support your browser.

GOAL showed more patients treated with salmeterol and fluticasone propionate as a fixed-dose combination achieved asthma control than patients treated with inhaled corticosteroid (ICS) alone and this control was attained at a lower corticosteroid dose. The study showed that doubling the inhalations of each strength of the salmeterol and fluticasone propionate fixed-dose combination for up to 14 days resulted in a small increase in β agonist-related adverse events (tremor; 1 patient [1%] vs 0, palpitations; 6 [3%] vs 1 [<1%], muscle cramps; 6[3%] vs 1 [<1%]) and a similar incidence of inhaled corticosteroid-related adverse events (e.g. Both hoarseness and incidence of mouth and throat candidiasis may be relieved by rinsing the mouth with water and/or brushing the teeth after using the product. The small increase in β agonist-related adverse events should be taken into account if doubling the dose of the salmeterol and fluticasone propionate fixed-dose combination is considered by the physician in adult patients requiring additional short-term (up to 14 days) inhaled corticosteroid therapy.The Salmeterol Multi-center Asthma Research Trial (SMART) was a 28-week US study that evaluated the safety of salmeterol compared to placebo added to usual therapy in adult and adolescent subjects. Salmeterol and fluticasone propionate should be used with caution in patients with severe cardiovascular disorders or heart rhythm abnormalities and in patients with diabetes mellitus, thyrotoxicosis, uncorrected hypokalaemia or patients predisposed to low levels of serum potassium.There have been very rare reports of increases in blood glucose levels (see section 4.8) and this should be considered when prescribing to patients with a history of diabetes mellitus.As with other inhalation therapy paradoxical bronchospasm may occur with an immediate increase in wheezing and shortness of breath after dosing. Taking more medication will not improve the symptoms; rather they may cause poisoning or serious side-effects. GLENMARK PHARMACEUTICALS LTD AIRTEC SF 500MG ROTACAPS 1 Units / pack . It is an age-old condition which has been creating problems for people for a long time. Combinations should be avoided unless the benefit outweighs the potential increased risk of systemic corticosteroid side-effects, in which case patients should be monitored for systemic corticosteroid side-effects.Co-administration of ketoconazole (400 mg orally once daily) and salmeterol (50 micrograms inhaled twice daily) in 15 healthy subjects for 7 days resulted in a significant increase in plasma salmeterol exposure (1.4-fold Cmax and 15-fold AUC). Ans: Seroflo 250 Inhaler is used to relieve symptoms like shortness of breath, chest tightness, wheezing, coughing, etc.caused by asthma and chronic obstructive pulmonary disease (COPD). Do not remove the canister from the plastic casing.3.