Hypokalemic Periodic Paralysis • Acute paralysis : Oral KCl (0.2–0.4 mmol/kg) every 30 min • Muscle strength and ECG should be monitored • IV therapy rarely required (e.g., when swallowing problems or vomiting is present) • Avoid potassium in dextrose solution • Mannitol is … 0000008606 00000 n
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General Pathology: Early; During attacks of weakness Vacuoles Internal; Sharp borders; Contents: Clear or Amorphous debris; Tubular aggregates.
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A progressive degenerative myopathy has been well described in hypokalemic periodic paralysis but is not as widely recognized in hyperkalemic periodic paralysis. 0000003708 00000 n
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Objective To map the phenotypic spectrum in 55 individuals with mutations in CACNA1S known to cause hypokalemic periodic paralysis (HypoPP) using medical history, muscle strength testing, and muscle MRI. 0000006637 00000 n
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Many levels stay the same and should not be used as a guideline for diagnosis of an episode. Phillip Wong, MB BS. 0000016185 00000 n
hypokalemic periodic paralysis
Scribd will begin operating the SlideShare business on September 24, 2020 Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. The phenotype is determined by the type of functional defect brought about by the mutations, rather than the channel effected, because the contrary phenotypes hyperkalemic periodic paralysis (HyperPP) and hypokalemic periodic paralysis (HypoPP) may be caused by point mutations in the same gene. 0000015205 00000 n
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