aciclovir fda

Acyclovir could be made use of by pregnant females, as it's been categorized as FDA pregnancy classification B (not expected to trigger injury to a coming kid). 59 23 0000000016 00000 n Aciclovir (ACV), also known as acyclovir, is an antiviral medication. 0000020608 00000 n 0000006317 00000 n 0000005279 00000 n 0000000756 00000 n Drug Resistance: Resistance of HSV and VZV to acyclovir can result from qualitative and quantitative changes in the viral TK and/or DNA polymerase. 0000001926 00000 n 2, magnesium stearate, microcrystalline cellulose, povidone, and sodium starch glycolate. Recommended Mar 2012; Revised Feb 2019, Sept 2019 . 9th ed. Avoid sexual intercourse or use a latex condom to prevent spreading the virus to others.Use the medication as soon as you remember. AIDSinfo provides the following drug label solely as an example of the labels available for acyclovir. whole body infection, brain infection, persistent pain after sore healing).Additionally, aciclovir is sometimes used to treat eczema herpeticum (a skin infection caused by the herpes virus), to treat and prevent herpes infections of the skin, eyes, nose, and mouth in patients with human immunodeficiency virus (HIV), and to treat oral hairy leukoplakia (condition that causes hairy white or gray-colored patches on the tongue or inside of the cheek).Nevertheless, it is important that you talk to your doctor about the possible risks of using this drug for your particular condition.Aciclovir comes in various forms: as a tablet (200 mg and 400 mg), topical cream (5%), intravenous injection (25 mg/mL) and ophthalmic ointment (3%).Use this medication exactly as it was prescribed for you. The only major urinary metabolite detected is 9-carboxymethoxymethylguanine accounting for up to 14.1% of the dose in patients with normal renal function.

Acyclovir Tablets are formulations for oral administration. Do not take this medication without telling your doctor if you are breast-feeding a baby.Herpes infections are contagious and you can infect other people, even while you are being treated with aciclovir.

For their discovery, Hitchings and Elion shared the 1988 Nobel Prize for medicine with the British pharmacologist Sir James Whyte Black (1924-).Aciclovir (INN) or acyclovir (USAN, former BAN) is a guanine analogue antiviral drug used most commonly to treat outbreaks of herpes simplex on the skin (mouth, lips, genitals, anus), outbreaks of shingles (herpes zoster), and chickenpox. %cFAA!�4��ZXJ��H�6��(#��'�b�ÔxX�curT��3�-�/.��:��}tU7�� 9x�0� o�!�� a��0 A�E� 0000012156 00000 n

0000001313 00000 n It is primarily used for the treatment of herpes simplex virus infections, chickenpox, and shingles. Aciclovir was patented in 1974, and approved for medical use in 1981.Aciclovir taken by mouth does not appear to decrease the risk of pain after shingles.Aciclovir is recommended by the CDC for treatment of varicella during pregnancy, especially during the second and third trimesters.Aciclovir is excreted in the breast milk, therefore it is recommended that caution should be used in breast-feeding women. Please note that aciclovir will not treat a viral infection such as the common cold or flu.Lesions caused by herpes viruses should be kept as clean and dry as possible. xref 0000001505 00000 n startxref A prescription is required for this medicine.This medicine was produced in the early 1950s to treat herpes infections by two American biochemists, George Hitchings (1905-) and Gertrude B. Elion (1918-). 0000002805 00000 n In people with frequent outbreaks, acyclovir is used to help reduce the number of future episodes.Acyclovir is an antiviral drug. endstream endobj 73 0 obj<>stream Public Health Foundation; 2006 Jan:171-92Gartner LM, Morton J, Lawrence RA, et al, "Breastfeeding and the Use of Human Milk," GlaxoSmithKline. H��V�n�8}�W�iA+R�.�i�Y`�"�`�}`e%�B��΢?�o�3��.Z }([�8�33�~��ֈ�y�Y�i+�h��)>X�e^�f�H�#�MK?�,�P�ߤ��1�.KT�4�(3�M�u��6��*#��y��TI��G)�o��+��*��{U�B��yT�q�i'o�8k��j~_�8N�T1�Y�O¨��?�?��ӕ�9�c�\�5[0��ꢂ�ZW��aa��m�X�z��;5y�@��@&(a�s�E��#��k-��Y�VAP~e��a��O��S�L��+f�E��^%��Ӭ�$��Ɂ�]|�c�G��C�aQ2�?�j��+5�ŵ��Y��Z�#�9G�t�gu�3�k�\)RmMvJД/�%Q(d�&� :o��D a�N��n�1��r:+~��,^�+�W��u9~�X�_�1l�v??u#��J�n�a�#�v2�w��M�HN��t-�=�?yը!�T#��r٣pN�J��P/:;�dd��S��T�h\�!U! It is primarily used for the treatment of herpes simplex virus infections, chickenpox, and shingles. Chickenpox (2 to <18 years of age) 20 mg/kg 3 times daily for 5 days; not to exceed 1 gram 3 times daily Valacyclovir oral suspension (25 mg/mL or 50 mg/mL) can be prepared from The medicine must be given slowly through an IV infusion, and can take at least 1 hour to complete.You may be given instructions on how to use your injections at home. Aciclovir, also known as acyclovir, is an antiviral medication. Acyclovir is also sometimes used to treat eczema herpeticum (a skin infection caused by the herpes virus) to treat and prevent herpes infections of the skin, eyes, nose, and mouth in patients with human immunodeficiency virus (HIV), and to treat oral hairy leukoplakia (condition that causes hairy white or gray-colored patches on the tongue or inside of the cheek). 0000007127 00000 n