h��Ymo�8�+�K�C:"E�Pp��m���v�|Pl��Ֆ���6��o��,ɒc'ٽ�C������m��0�9㎏w���w�� 163 0 obj <>stream Intramuscular administration is not recommended.Note: The dosage recommendations for glaucoma and epilepsy differ considerably from those for congestive heart failure, since the first two conditions are not dependent upon carbonic anhydrase inhibition in the kidney which requires intermittent dosage if it is to recover from inhibitory effect of the therapeutic agent.Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit.The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical judgment. By inhibiting the reaction catalysed by this enzyme in the renal tubules, acetazolamide increases the excretion of bicarbonate and of cations, chiefly sodium and potassium, and so promotes alkaline diuresis.
An example is reported crystallization in high-concentration cefazolin sodium after reconstitution with normal saline.10 . l5@��D� �5@�ODl��,��++�ȏc`bdxd100�t�?��3
Reconstituted solutions retain their physical and chemical properties for 12 hours at room temperature 20° to 25°C (68° to 77°F).The direct intravenous route of administration is preferred. Neither GlobalRPh Inc. nor any other party involved in the preparation of this program shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user's use of or reliance upon this material. Each 500 mg vial containing sterile acetazolamide sodium should be reconstituted with at least 5 mL of Sterile Water for Injection prior to use.
� �4|v�ƻ�\�ŻfRҸ�d@��$��y��;g�w�ɴG�i���k�{������\�9�wIA�r�:�H Ԟ���!�U�.��I�hb'�$R���X"٣%i��$�H�yǧ�=�ġ��F��|2`�vpe��LrE#�IE�T.��tQ�)W���Ҵ���C�f���g�V40M�8nI�dN�3��6�+���>|�Ao>��#����&���p��qO��rp -Gradually reduce the dose of the uricosuric agent while increasing the allopurinol dose to a dose that maintains a normal serum uric acid level; this may take several weeks. endstream endobj startxref The study is created by eHealthMe based on reports of 127 people who take Acetazolamide and Allopurinol from the Food and Drug Administration (FDA), and is updated regularly. Reconstituted solutions retain their physical and chemical properties for 3 days under refrigeration at 2° - 8° C (36° - 46° F), or 12 hours at room temperature 15° - 30° C (59° - 86° F).
Summary: Drug interactions are reported among people who take Acetazolamide and Allopurinol together. • Normal saline reconstitution of medications for IV push administration may produce solutions at or near the solution’s saturation point.
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