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The Brazilian consensus recommends a short-term treatment course with clarithromycin, amoxicillin and proton-pump inhibitor for the eradication of Sixty patients with peptic ulcer diagnosed by upper digestive endoscopy and The eradication rate was 38% per intention to treat and 41% per protocol. Unable to load your delegates due to an error 1998, 32: 785-93.
Draft of manuscript: FMS. The typical dosage is 30 mg/kg of body weight taken as a single dose, or 10 mg/kg of body weight once per day for 3 days.
Article in PortugueseLourenço LG, Hamada GS: Gastric cancer in Brazil. Am J Gastroenterol. The aim of our study was to establish whether one‐week triple therapy regimen (omeprazole, amoxicillin, azithromycin) with low dose (2 × 20 mg/day) or high dose omeprazole (2 × 40 mg/day) is more effective in curing H. pylori infection in patients with active duodenal ulcer disease.. Methods.
This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. 1987, 31: 1939-47.Blandizzi C, Malizia T, Gherardi G, Costa F, Marchi S, Marveggio C, Natale G, Senesi S, Bellini M, Maltinti G, Campa M, Tacca MD: Gastric mucosal distribution and clinical efficacy of azithromycin in patients with Di Mario F, Dal Bó N, Grassi AS, Cannizzaro O, Armuzzi A, Gasbarrini A, Addolorato G, Gasbarrini GB: Azithromycin for the cure of Caselli M, Trevisani L, Tursi A, Sartori S, Ruina M, Luzzi I, Gaudenzi P, Alvisi V, Gasbarrini G: Short-term low-dose triple therapy with azithromycin, metronidazole and lansoprazole appears highly effective for the eradication of Chey WD, Fisher L, Barnett J, Delvalle J, Elta GH, Hasler WL, Nostrant T, Palaniappan J, Scheiman J: Low-versus high-dose azithromycin triple therapy for Helicobacter pylori infection.
Cienc Saude Coletiva.
Few adverse effects were observed and treatment compliance was high.Despite its low cost and high compliance, the low eradication rate does not allow the recommendation of the triple therapy with azithromycin as an adequate treatment for Several therapy courses have been employed in the eradication of the bacterium, with the use of drugs such as bismuth, clarithromycin, amoxicillin, furazolidone, nitroimidazole compounds and proton pump inhibitors, in assorted combinations [The search for low-cost and higher efficacy with fewer adverse effects, that can allow higher compliance to The macrolides are among the antibiotics that used alone, present high rates of bacterium eradication, with few adverse effects and simple regimen, especially clarithromycin [In Brazil, the triple therapy with amoxicillin and clarithromycin, associated to a proton pump inhibitor for 7 days, has attained good eradication rates [Azithromycin, a macrolide with a long term action [The Public Health services in our country do not provide any eradication treatment for The inclusion criteria were: peptic ulcer diagnosed by upper digestive endoscopy, and The exclusion criteria were: age younger than 16 or older than 90 years, chronic use of acetylsalicylic even at low doses, or other anti-inflammatory drugs, previous use of macrolides, use of antibiotics or chemotherapeutic drugs in the 4 weeks prior to study enrollment, having complicated peptic ulcer, pyloric stenosis, previous gastric surgery, erosive esophagitis, to be pregnant or breastfeeding, having consumptive diseases or not controlled renal, heart or hepatic failure, having been previously treated for The eradication treatment was carried out with omeprazole 20 mg and azithromycin 500 mg in a single daily dose taken in fasting condition in the morning, associated with amoxicillin 500 mg, taken three times a day immediately after meals, for six days.The adverse effects and the compliance were documented on the first day after the end of the treatment. Ache, Braz. 2009 Dec 28;15(48):6102-10. doi: 10.3748/wjg.15.6102.Silva FM, Eisig JN, Teixeira AC, Barbuti RC, Navarro-Rodriguez T, Mattar R.BMC Gastroenterol.