Opioid rotation: the science and the limitations of the equianalgesic dose table. This is an unprecedented time. PO 7.5 mg Levorphanol 6-8 h 12-16 h IM/IV/SC 2 mg PO 4 mg Meperidine æ: 2-4 h 3-4 h IM/IV/SC 75 mg PO 300 mg Methadone 4-6 h 15-30 h IM/IV/SC 1-10 mg § Medline Short term: 5-10mg Chronic use: 1-4 mg (2 mg) PO 2 - 20 mg § Medline Short term use: 20 mg Chronic dosing: 2-4 mg (3mg) Morphine 3-6 h 1.5-3 h IM/IV/SC 10 mg PO is converted to the active thyroid hormone, L-triiodothyronine (T).
This updated dose conversion is based on recent literature which has shown that the bioavailability of levothyroxine is estimated to be around 79-81 percent. PMID 17299011. [May cause GI upset, bleeding, ulceration, perforation; take with food or milk to minimize GI upset.]
Lexi-Drugs. Historically, when converting from a parenteral to enteral route, the dose conversion was 1:2.
Opioid conversions in acute care. MOTRIN tablets are indicated for relief of mild to moderate pain.
This updated dose conversion is based on recent literature which has shown that the bioavailability of levothyroxine is estimated to be around 79-81 percent. IM: 60 mg x 1 or 30 mg q6h (maximum daily dose: 120 mg).
1. IV to PO conversion.
290.914.916.010.
Drug Usual IV Dose* Approximate PO Dose* PO to IV Considerations/Comments Reference digoxin 0.1 -0.4 mg IV Q 24 H 0.125 -0.5 mg PO Q 24 H Oral bioavailability about 80% for tablets and liquid 1,2 dimenhyDRINATE 25-50 mg IV 25-50 mg PO Conversion of IV to PO is 1:1 Lexicomp. Guidelines for the Treatment of Hypothyroidism: Prepared by the American Thyroid Association Task Force on Thyroid Hormone Replacement. Oral dosing is intended to be a continuation of IM/IV therapy only.
J Pain Symptom Manage. Available at: http://online.lexi.com. Common IV to PO Drug Conversions 1) Metoprolol 1:2.5 2) Diltiazem Oral Dose(mg/day) = [ rate (mg/hr) x 3 + 3 ] x 10 3) Digoxin 0.75:1 4) Levothyroxine 0.75:1 5) Aminophylline to Theophylline 1:0.8 6) Ciprofloxacin 1:1.25 #IVtoPO #Drug #Conversion #Pharmacology #Common #Intravenous #Oral Levothyroxine is available in both an oral and intravenous (IV) formulation.
pharmacist for any questions about appropriate conversion doses.
3 Based on this data, the ATA Guidelines and Lexicomp recommend administering an IV dose that is 75 percent of the oral dose when converting from a parenteral to enteral route. Oral: 20 mg, followed by 10 mg every 4 to 6 hours (Max 40 mg/day).
MOTRIN tablets are also indicated for the treatment of primary dysmenorrhea. The Steroid Conversion Calculator converts steroid dosages using dosing equivalencies.
MOTRIN tablets are indicated for relief of the signs and symptoms of rheumatoid arthritis and osteoarthritis.
Based on this data, the ATA Guidelines and Lexicomp recommend administering an IV dose that is 75 percent of the oral dose when converting from a parenteral to enteral route. Juvenile rheumatoid arthritis: 30-50 mg/kg/24 hours divided every 8 hours; start at lower end of dosing range and titrate upward (maximum: 2.4 g/day) Analgesia/pain/fever/dysmenorrhea: 200-400 mg/dose every 4-6 hours (maximum daily dose: 1.2 g, unless directed by physician) OTC labeling (analgesic, antipyretic): 200 mg every 4-6 hours as needed (maximum: 1200 mg/24 hours) For relief of the signs and symptoms of osteoarthritis Rheumatoid arthritis: 1200 mg once daily; a one-time loading dose of up to 1800 mg/day or 26 mg/kg (whichever is lower) may be given Maximum daily dose: 1800 mg or 26 mg/kg (whichever is lower) in divided doses National Institutes of Health, U.S. National Library of Medicine, initial, 400 mg orally three times a day for 1-2 weeks. conversion.
Jonklaas J, Bianco AC, Bauer AJ, et al. At Sparrow, we have updated the parenteral to enteral drug conversion policy to include the new levothyroxine conversion to match the updated guidelines.There are currently no comments, be the first to post one. The dose conversion has been updated in the ATA Guidelines, which recommend a dose conversion of 0.75:1 when converting from a parenteral to enteral route. ... Pharmacist –initiated IV to PO conversion program of antimicrobials.