Anxiety associated with depression: Immediate release: Average dose required: 2.5-3 mg/day in divided doses. Conversion of IV Midazolam. The benzodiazepine conversion calculator adjusts doses between converting oral benzodiazepines. Supplied: Capsule (delayed release): 20 mg, 40 mg. Granules - for oral suspension: 20 mg, 40 mg. Injection (powder for reconstitution): 20 mg, 40 mg. Dosing: Healing of erosive esophagitis: Oral: Initial: 20-40 mg once daily for 4-8 weeks. Midazolam, lorazepam, diazepam, and phenobarbital are available in both parenteral and oral formulations.Because published benzodiazepine dose conversions are based on oral administration, parenteral formulations may not use the same conversion ratio. It is the dedication of healthcare workers that will lead us through this crisis. Select drug alprazolam (Xanax) chlordiazepoxide (Librium) clonazepam (Klonopin) clorazepate (Tranxene) diazepam (Valium) estazolam (ProSom) flurazepam (Dalmane) lorazepam (Ativan) oxazepam (Serax) … The benzodiazepine conversion calculator adjusts doses between converting oral benzodiazepines. These wide ranges of confidence highlight the lack of firm, evidence-based literature supporting specific conversion ratios.In addition to an overall lack of evidence to support specific conversions, there are a number of other limitations that should be recognized:Given the numerous issues with benzodiazepine equivalence, the importance of reasonable clinical judgment, clinical experience, appropriate patient monitoring, and dose titration are of even greater significance.Most benzodiazepines included in this calculator are only available as oral dosage forms.
Enter your email address and we'll send you a link to reset your password.Creating an account is free, easy, and takes about 60 seconds.Short acting: 6-12 hours (ALPRAZolam, oxazepam, triazolam).Intermediate acting: 12-24 hours (LORazepam, temazepam).Long acting: >24 hours (chlordiazePOXIDE, diazePAM, clonazePAM).This calculator does not account for age, organ function, and inter-patient variability that may alter the pharmacokinetics, peak effect, and duration of action.Selecting doses on the lower end of the reported range may result in lower risk of unwanted oversedation.Dosing conversions may not be adequate when treating such conditions as status epilepticus or alcohol withdrawal. Benzodiazepine Equivalents Conversion Calculator. Unlike All benzodiazepine conversions used in this calculator are based on published equipotent dose estimates.Due to discrepancies in the literature, many benzodiazepine conversions may have a potential conversion range that is extremely variable (eg, by a factor of 10x or greater).
3) Divide total daily dose of diazepam (can be given IV or PO) by 4 to get Q6h dosing 4) Start diazepam and decrease IV midazolam infusion by 50% with 1st dose of IV or enteral diazepam. Subcategory of 'Diagnosis' designed to be very sensitiveDisease is diagnosed: prognosticate to guide treatmentProvides equivalents between different benzodiazepines.This calculator should be used as a reference for oral benzodiazepine conversions.
benzodiazepine, neuromuscular blockade, NSAID, and steroid drug conversion factors Opioid Drugs Equivalent Dose IV morphine 1 mg IV fentanyl 0.01 mg IV hydromorphone 0.15 mg Oral oxycodone 3 mg IV nalbuphine 1 mg Oral codeine 20 mg Benzodiazepines Equivalent Dose IV midazolam 1 mg IV lorazepam 0.5 mg
While barbiturates do share similar pharmacology to benzodiazepines, they have a more concerning safety profile with a higher incidence of respiratory depression. Background info - dosing information: Alprazolam (Xanax ®) Dosing (Adults): Anxiety: Immediate release: Effective doses are 0.5-4 mg/day in divided doses; the manufacturer recommends starting at 0.25-0.5 mg 3 times/day; titrate dose upward; maximum: 4 mg/day. Disease-state specific guidelines should be utilized.
ClinCalc: 5) Cease IV midazolam infusion with 2nd dose IV or enteral diazepam Conversion of IV … This calculator only accounts for differences in bioavailability with midazolam. Unlike nearly all other benzodiazepine conversions, the conversion between intravenous midazolam and lorazepam has been well studied in mechanically ventilated patients.