2017 [cited 30 August 2017]. By mouth. Medlineplus.gov. Rare side effects include bone marrow suppression, pancreatitis, hemolytic anemia, hematuria, upper airway infections, and skin rash. The rectal form of this medicine is not recommended for use in children and adolescents.Caution is advised while using this medicine in elderly patients due to the increased risk of severe adverse effects.Use of NSAIDs along with this medicine may increase the risk of renal impairment. For decades, mesalamine has been a first-line therapy for ulcerative colitis and Crohn's disease (collectively known as inflammatory bowel disease, or IBD). By continuing you agree to the Copyright © 2020 Elsevier B.V. or its licensors or contributors. Asacol is available in 400-mg capsules. It has an antiinflammatory effect on bowel mucosa with inhibition of the arachidonic acid pathway. Hydrochlorothiazide is also used to treat fluid retention (edema) in people with congestive heart failure, cirrhosis of the liver, or kidney disorders, or edema caused by taking steroids or estrogen. All the risks and benefits should be discussed with the doctor before taking this medicine.This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Symptomatic and supportive therapy is warranted in case of an overdose with delayed-release tablets of Mesalazine. It has proved to be safe and effective in patients who are intolerant or allergic to sulfasalazine. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. Dailymed.nlm.nih.gov. See detailed T&CMesalazine is an anti-inflammatory drug used in the treatment of ulcerative colitis, a condition characterized by swelling and scarring of the colon and rectum. Mesalamine is a relatively weak anti-inflammatory drug, but it also has minimal adverse effects in IBD patients. The release characteristics of mesalazine in different dosage forms … Close monitoring of renal function may be required based on the clinical condition.This is not an exhaustive list of possible drug interactions. Some reports may have incomplete information.Patients can bring a copy of the report to their healthcare provider to ensure that all drug risks and benefits are fully discussed and understood. It doesn’t have a brand-name version. Dailymed.nlm.nih.gov. * Approximation only. ScienceDirect ® is a registered trademark of Elsevier B.V.URL: https://www.sciencedirect.com/science/article/pii/S009954280860756XURL: https://www.sciencedirect.com/science/article/pii/B9780128094020000022URL: https://www.sciencedirect.com/science/article/pii/S0378608010320368URL: https://www.sciencedirect.com/science/article/pii/B978044462635600036XURL: https://www.sciencedirect.com/science/article/pii/S0076687914000998URL: https://www.sciencedirect.com/science/article/pii/S0378608008000366URL: https://www.sciencedirect.com/science/article/pii/B9781556644801500484URL: https://www.sciencedirect.com/science/article/pii/S0378608005804581URL: https://www.sciencedirect.com/science/article/pii/B9780128113882000014URL: https://www.sciencedirect.com/science/article/pii/B9780444537416000362Analytical Profiles of Drug Substances and ExcipientsAnalytical Profiles of Drug Substances and ExcipientsIndications and Preoperative Medical Management of Ulcerative Colitis Patients Undergoing Pouch SurgeryA worldwide yearly survey of new data in adverse drug reactions and interactions A 17-year-old man developed a cough, dyspnea, and pleuritic chest pain after taking Distrutti, Sediari, Mencarelli, Renga, Orlandi, & Russo, 2006A worldwide yearly survey of new data and trends in adverse drug reactions and interactionsAaron Brzezinski MD, FRCP(C), Bret A. Lashner MD, MPH, in Current Therapy in Colon and Rectal Surgery (Second Edition)In an open multicenter study of 18 patients with Crohn's disease and 29 patients with ulcerative colitis, Overview of Diagnosis and Medical Treatment of Inflammatory Bowel DiseasesInterventional Inflammatory Bowel Disease: Endoscopic Management and Treatment of ComplicationsA worldwide yearly survey of new data in adverse drug reactionsScienceDirect ® is a registered trademark of Elsevier B.V. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. The study is created by eHealthMe based on reports of 302 people who take Asacol and Hydrochlorothiazide from the FDA, and is updated regularly. 2017 [cited 30 August 2017]. All rights reserved. Available from: DailyMed - Mesalamine suspension [Internet]. Available from: DailyMed - Canasa - Mesalamine suppository [Internet]. Common side effects of Asacol include: mild nausea, vomiting, ; stomach cramps, ; diarrhea, Drug interactions are reported among people who take Pentasa and Hydrochlorothiazide. The side effect profile of 5-aminosalicylates or mesalamines is favorable. Hydrochlorothiazide is used to treat high blood pressure (hypertension). Mesalamines are excreted to urine and feces.