Purpose: To describe the use of intravenous immune globulin (IVIG) in an 8-year-old girl with Patients and Methods: An 8-year-old girl had fever, rash,
Am J Case Rep. 2020 Jan 30;21:e919828. An intermediate epoxide metabolite of phenytoin is suspected as the cause of platelet destruction, which may occur via a complement-antibody reaction.
Epub 2009 Sep 18.Brain Inj.
Thrombocytopenia is a rare isolated complication of phenytoin therapy. Pediatr Neurol 1986;2:99-101. Cimetidine has also been reported to cause eosinophilia, which was confirmed by rechallenge. ObjectiveTo describe a patient with severe thrombocytopenia induced by the administration of phenytoin for prevention of seizures.
Respiratory. Our patient experienced some confusion as a possible consequence of her thrombocytopenia, but no long-term sequelae … Place a little lettuce thrombocytopenia with metformin sliced tomato and the lower number in grams of protein per day). The probable autoimmune etiology distinguishes this syndrome from other phenytoin-induced blood …
doi: 10.12659/AJCR.919828.Wang H, Gao J, Lassiter TF, McDonagh DL, Sheng H, Warner DS, Lynch JR, Laskowitz DT.Neurocrit Care.
Most described cases in the literature occurred following phenytoin initiation. Atypon Please enable it to take advantage of the complete set of features! Learn more about the causes, symptoms, and treatment of thrombocytopenia.
Conclusions: Phenytoin hypersensitivily can present with throm-bocytopenia and leukopenia. phenytoin-induced thrombocytopenia with potentially serious complications, including death, in a small number of patients (2). Giving 1 g kg −1 of intravenous immunoglobulin has been associated with a rapid increase in the platelet count, and should be considered [ 3 ]. The item(s) has been successfully added to "
Thrombocytopenia is a rare isolated complication of phenytoin therapy. doi: 10.12659/AJCR.919828.Park BD, Kumar M, Nagalla S, De Simone N, Aster RH, Padmanabhan A, Sarode R, Rambally S.Transfus Apher Sci. Scheuerman O, Nofech-Moses Y, Rachmel A, Ashkenazi S.Pediatrics. Results: The thrombocytopenia improved dramatically after IVIG therapy. She was treated with I g/kg of IV1G. Please try after some time.Your message has been successfully sent to your colleague.Some error has occurred while processing your request. to maintaining your privacy and will not share your personal information without
There was an increase in immature neutrophils but no abnormalities were present in other cell lines.
Unable to load your collection due to an error … Our patient experienced toxicity following an increase in dose, probably accentuated by azithromycin treatment. 65 A raised eosinophilia count was first noted two weeks after ranitidine 300mg daily was initiated and resolved after it had been discontinued. By continuing you agree to the Copyright © 2020 Elsevier B.V. or its licensors or contributors. However, it may b … Frequency not reported: Leukopenia, thrombocytopenia, thrombocytopenia purpura. Wolters Kluwer Health
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We report severe phenytoin-induced thrombocytopenia in a patient with an intracerebral haemorrhage (ICH) secondary to a left parietal arteriovenous malformation (AVM) rupture. Clipboard, Search History, and several other advanced features are temporarily unavailable. These doctors to establish whether inhaled. The treatment of phenytoin-induced thrombocytopaenia is discontinuation of phenytoin and, if the patient has associated life-threatening haemorrhage, platelet transfusion. ObjectiveTo describe a patient with severe thrombocytopenia induced by the administration of phenytoin for prevention of seizures. Please try after some time.Get new journal Tables of Contents sent right to your email inbox 800-638-3030
Antiepileptic drug-induced blood …
Recovery was complete after drug therapy was discontinued. Anticonvulsant medications, also known as anti-epileptics are drugs used to treat seizures and sometimes, nerve pain disorders. Please try again soon.
There was an increase in immature neutrophils but no abnormalities were present in other cell lines. Treatment with IVIG was associated with a rapid rise in the platelet count in the patient in this report.
Journal of Pediatric Hematology/Oncology:
Drug-induced immune thrombocytopenia is a relatively uncommon adverse reaction caused by drug-dependent antibodies. Phenytoin-induced thrombocytopenia is considered a rare event, but it has life-threatening consequences.