Clin Epidemiol 10:289–298Fourcade R, Lacoin F, Slama A, Gaudin A, Le Fur C, Michel E, Sitbon, Cotté (2010) UP-1.09: impact of benign prostatic hyperplasia (BPH) on medically treated patients' quality of life. J Clin Endocrinol Metab 89:2179–2184Wessells H, Roy J, Bannow J et al (2003) Incidence and severity of sexual adverse experiences in finasteride and placebo-treated men with benign prostatic hyperplasia.
Int J Clin Pract 70:1012–1018Johannes CB, Araujo AB, Feldman HA, Derby CA, Kleinman KP, McKinlay JB (2000) Incidence of erectile dysfunction in men 40 to 69 years old: longitudinal results from the Massachusetts male aging study. With reports submitted from the United States and other countries, FAERS is a much larger database than DAEN, containing well over two million ADR reports compared to 70,000 ADR reports in our previous analysis. FDA Adverse Event Reporting System (FAERS): Latest Quarterly Data Files. You can also search for this author in Fertil Steril 107:301–304Erectile dysfunction epidemiology (2003) Int J Impot Res 15(Suppl 7):S2–4Morin L, Johnell K, Laroche ML, Fastbom J, Wastesson JW (2018) The epidemiology of polypharmacy in older adults: register-based prospective cohort study. 2017 Jul;5(4):671-678. doi: 10.1111/andr.12353. BC: protocol/project development, and manuscript writing/editing.The author(s) declare that they have no conflict of interest.The data used in this study are de-identified and publicly available FAERS data. J Clin Endocrinol Metab 75:484–488Clark RV, Hermann DJ, Cunningham GR, Wilson TH, Morrill BB, Hobbs S (2004) Marked suppression of dihydrotestosterone in men with benign prostatic hyperplasia by dutasteride, a dual 5α-reductase inhibitor. Br J Psychol 86(Pt 3):337–344Baas WR, Butcher MJ, Lwin A et al (2018) A review of the FAERS data on 5-α reductase inhibitors: implications for postfinasteride syndrome. Asian J Urol 4:148–151Eisenberg ML, Meldrum D (2017) Effects of age on fertility and sexual function. The causality and the rate of AEs are not certain based on the FAERS data and future prospective studies are necessary to determine the true rates.Immediate online access to all issues from 2019.
MBH: data collection/management/analysis, and manuscript writing.
Reports identified one or more adverse effects, along with all concurrent medications. Methods: Following pre-processing of FAERS data by elimination of duplicated records as well as adjustments to standardize drug names, reports involving haloperidol, olanzapine, quetiapine, clozapine, ziprasidone, risperidone, and aripiprazole were analyzed in children (age 0-12). Version 04/18/2012. The frequency procedure in SAS was utilized to summarize rates of AEs between various dosages of each drug.A total of 16,014 case reports were obtained.
Subscription will auto renew annually.Liu L, Zhao S, Li F et al (2016) Effect of 5α-reductase inhibitors on sexual function: a meta-analysis and systematic review of randomized controlled trials. To investigate the sexual, physical, and mental adverse effects associated with exposure to 5-alpha reductase inhibitors (5ARIs). Objectives: Data mining algorithms have been developed for the quantitative detection of drug-associated adverse events (signals) from a large database on spontaneously reported adverse events. Version 03/2013. Epub 2015 Oct 21.Corona G, Tirabassi G, Santi D, Maseroli E, Gacci M, Dicuio M, Sforza A, Mannucci E, Maggi M.Andrology.
Clipboard, Search History, and several other advanced features are temporarily unavailable. KH: data collection/management/analysis, and manuscript writing. Ther Clin Risk Manag 7:337–344Golan DETJA, Armstrong EJ, Armstrong AW (2011) Principles of pharmacology: the pathophysiologic basis of drug therapy, 3rd revised international ed edition ed. FAERS data containing finasteride and dutasteride reports were analyzed from January 2000 to April 2019. Cases of monotherapy of finasteride or dutasteride were identified. Version 06/04/2018. Drug and device reports can be found in the FDA Adverse Event Reporting System (FAERS) Public Dashboard. 2013 May;1(1):24-41. doi: 10.1002/smrj.3.
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