3177 Japanese men with androgenetic alopecia participated in this study in order to observe the safety and efficacy of finasteride 1 mg tablet daily from 2006 – 200923 out of 3177 men experienced adverse reaction (study doesn´t specify whether these side effects were of sexual nature or not)No follow-up examination of many patients in this study. Their ultimate goal is to have Finasteride removed from the market completely. Here is a brief summary I especially liked on this topic coming from the The higher the sample size of observed subjects in any study, the higher the statistical significance the study will have.Statistical significance is the likelihood that a relationship between two or more variables is caused by something other than chanceA statistically significant experiment means that you can be almost sure that the results you observed are reliable and not distorted by selection bias for example.The smaller the sample size, the less reliable the results are being considered from statistical point of view.Statistical significance can be only present by studies which were done on large enough samples sizes. This post also gives you some useful suggestions on how to minimize the potential side effects of Finasteride while using it for successful hair loss management long – term.Out of all 14 studies I was able to find on this topic, there are 4 studies which are suggesting the the occurrence of PFS is real and 8 studies suggesting safety of finasteride with no or minimal side effects of any kind. It is mandatory to procure user consent prior to running these cookies on your website.This website uses cookies to improve your experience while you navigate through the website. Sample sizes of 10, 20, 50 or even 100 are still considered to be very insignificant when it comes to statistical evaluation. Inhibitors of 5α-steroid reductase are drugs used to treat androgen-dependent conditions including prostate diseases and androgenic alopecia. We'll assume you're ok with this, but you can opt-out if you wish. Based on PFS foundation website there have been over 16,000 detected cases of post – finasteride syndrome and 63 known suicides between 2012 and 2020 so far.Which makes it around 2000 adverse reactions per year and 8 suicides per year.Finasteride has been approved for hair loss in 1997, which makes it the most frequently prescribed drug for treating hair loss with over 70.000.000 prescriptions between 2007 – 2017 (just in the USA) based on Don´t you think that if you randomly select 70.000.000 Americans and observe them for 10 years, you will realize that 63 of them may easily try to kill or actually kill themselves anyways because statistically, the occurrence of such event by a sample size of 70.000.000 million is very likely regardless of whether the whole sample have been on Finasteride or not.Testosterone levels in men treating with Finasteride for BPH (benign prostatic hyperplasia) decreased after taking Finasteride. Tolerance of finasteride: well.The sample size available for analysis decreased with time.120 patients, sexually active, randomly received finasteride 5 mg concealed as an “X” compound of proven efficacy for the treatment of BPH” for 1 yearGroup 1 (n=52) didn´t receive any information about potential sexual side effects related to this drug.Group 2 (n=55) received information about potential sexual side effects related to this drug ( erectile dysfunction, decreased libido, problems of ejaculation).Petients, who received the information about the potential side effects prior to the start of the treatment were more likely to experience sexual side effects (43.6%) as opposed to the group 2 (15.3%) – not knowing about the potential side effects.Small sample size of each group (52 and 55 subjects respectively).During 24 month period 424 men aged 41-60 years received finasteride 1 mg on hair growth/loss General tolerance of finasteride treatment was well and study doesn´t report about any adverse effects.How to take Finasteride, Dutasteride, Minoxidil and other topicals for effective hair loss prevention in 2020!This website uses cookies to improve your experience. The Post-Finasteride Syndrome (PFS) is a devastating condition characterized by the persistence and development of diverse sexual, neurological and physical side effects after discontinuation of 5-alpha reductase inhibitors such as finasteride and Dutasteride.