Approximately half of the infants in the district are born to Jewish parents, and half to Bedouin Muslim parents.The clinical, medication, and demographic data related to members of Clalit Health Services are aggregated in a Clalit Health Services database and can be accessed at the level of an individual member. 2017 Jun 14;357:j2563. Epub 2017 Dec 30.Persson M, Cnattingius S, Villamor E, Söderling J, Pasternak B, Stephansson O, Neovius M.BMJ.
The diagnoses are reviewed routinely by a trained medical secretary before entry into the database.The other electronic database at Soroka Medical Center that was used in the present study was the Demog-ICD9 database, which includes demographic and medical diagnoses during hospitalization, with medical diagnoses drawn directly from the medical records. ), and Obstetrics and Gynecology (E.S., A.W. Characteristics of mothers of the exposed group and of mothers of the unexposed group were compared with the use of the chi-square test or Fisher's exact test for categorical variables and Student's t-test for continuous variables. Please enable it to take advantage of the complete set of features! The rate of major congenital malformations among infants born to these mothers was 3.8% (29 infants), as compared with 4.9% (3834 infants) in the unexposed group (adjusted odds ratio, 0.76; 95% CI, 0.53 to 1.11).Metoclopramide has been extensively used for decades to treat nausea and vomiting in pregnant women, despite a lack of data on the safety of the drug in pregnancy. — all in Beer-Sheva, Israel; the Motherisk Program, Division of Clinical Pharmacology, Hospital for Sick Children, University of Toronto, and the BeMORE Collaboration, Toronto (G.K.); and the Department of Medicine, University of Western Ontario, London, Canada (G.K.).Address reprint requests to Dr. Gorodischer at the Soroka Medical Center, P.O. Unable to load your collection due to an error
2014 Feb 12;311(6):624. doi: 10.1001/jama.2013.285289.Ann Intern Med. Sep 3, 2020 2014 Feb 12;311(6):623-4. doi: 10.1001/jama.2013.285286.JAMA. A categorical multivariate logistic-regression model was constructed to determine whether greater exposure was associated with an increased risk of major congenital malformations. 2018 Sep;5(3):193-206. doi: 10.1007/s40801-018-0141-1.Orphanet J Rare Dis. Zofran is often used to prevent and treat nausea and vomiting during chemotherapy and after surgery. Higher rates of congenital malformations have been documented among Bedouins than among Jews, a finding that is possibly attributable to increased rates of consanguinity among Bedouins.A strength of our study, in contrast to previous studies,A limitation of our report is the possibility that some outcomes may have been misclassified, because the classification of outcomes was based on administrative data rather than on a review of medical records.
Peer-reviewed journal featuring in-depth articles to accelerate the transformation of health care delivery.Information, resources, and support needed to approach rotations - and life as a resident.Valuable tools for building a rewarding career in health care.Information and tools for librarians about site license offerings.The authorized source of trusted medical research and education for the Chinese-language medical community.The most trusted, influential source of new medical knowledge and clinical best practices in the world.The Safety of Metoclopramide Use in the First Trimester of PregnancyCharacteristics of Women to Whom Metoclopramide Was Dispensed in the First Trimester of Pregnancy and of Women to Whom It Was Not Dispensed.Odds Ratios for Adverse Outcomes after Intrauterine Exposure to Metoclopramide during the First Trimester, as Compared with Nonexposure.Odds Ratios for Major Congenital Malformations Associated with Exposure to Metoclopramide during the First Trimester of Pregnancy, According to Levels of Defined Daily Doses.Characteristics of Women to Whom Metoclopramide Was Dispensed in the First Trimester of Pregnancy and of Women to Whom It Was Not Dispensed.Odds Ratios for Adverse Outcomes after Intrauterine Exposure to Metoclopramide during the First Trimester, as Compared with Nonexposure.Odds Ratios for Major Congenital Malformations Associated with Exposure to Metoclopramide during the First Trimester of Pregnancy, According to Levels of Defined Daily Doses. 2016 Jan 5;315(1):58-67. doi: 10.1001/jama.2015.17844.Huybrechts KF, Hernández-Díaz S, Straub L, Gray KJ, Zhu Y, Patorno E, Desai RJ, Mogun H, Bateman BT.JAMA.
The Soroka Medical Center databases were linked by this single hospitalization number.