For acne, it is applied to the skin as a cream, gel or ointment. abdominal pain, nausea, vomiting and diarrhoea) and tretinoin (including teratogenesis in women of childbearing years) are expected. Management of Acne: A Report From a Global Alliance to Improve Outcomes in Acne Kang S, Voorhees JJ. Oral and parenteral administration of clindamycin has been reported to result in the appearance of clindamycin in breast milk. Ive aways suffered with my skin since i was about 16 years old. Ive tried every face product on earth to try and clear my skin from £100+ kits to cheap £2 supermarket washes, and nothing has helped until 2 weeks ago... Ive learned my skin is extremely sensitive to fragrance so ive had to start using 0% colour 0% fragrance Laundry liquid and softner which helped calm my skin down and also started to use The Body Shop Aloe Toner to help keep clear my scars all that along with my Treclin 1%/0.025% w/w gel and finally i can say skin is looking the best it ever has. Oral tretinoin has been shown to be teratogenic in rats, mice, hamsters, rabbits, monkeys and humans. Topical retinoids. The comedolytic activity is related to a normalisation of the desquamation of the follicular epithelium. I rarely got active spots unless it was like a week before I got my period. Individual decisions are advisable in severe cases.Treclin is indicated for external (dermatological) use only. I just wanted to post a review about Treclin 1%/0.025% w/w gel which i have started using for the past 2 weeks. The concomitant treatment with corticosteroids should be avoided.In vitro, antagonism has been demonstrated between erythromycin and clindamycin, synergy has been shown with metronidazole, both antagonistic and synergistic effects have been observed with aminoglycosides and agonistic action has been described with neuromuscular blocking agents.Increased coagulation tests (PT/INR) and/or bleeding, have been reported in patients treated with clindamycin in combination with a vitamin K antagonist (e.g. Application to sensitive areas of skin should be made with caution. The excipient butylhydroxytoluene (E321) may cause local skin reactions (e.g. This site uses cookies. Patient Info Name: Treclin 10 mg/g + 0.25 mg/g Gel. However, there could be individual factors (e.g. Treclin 10 mg/g + 0.25 mg/g Gel. Thus, this combination therapy targets multiple pathogenic factors: abnormal follicular keratinization, Patients with 20-50 facial acne inflammatory lesions (papules and pustules), 20-100 facial acne non-inflammatory lesions (open and closed comedones), two or fewer nodules (defined as an inflammatory lesion greater than or equal to 5 mm in diameter) and without cysts were included. Sign In or Sign Up as a New Member to Review a Product or Treatment; Trending items. © 2020 RealSelf, Inc. All rights reserved. Occasional gram-negative folliculitis has been reported during treatment with clindamycin 1% topical products. July 10, 2013, Ralph M. Trüeb. Post a Comment. Acne.org does not advertise. If excess application occurs accidentally or through over-enthusiastic use, the face should be gently washed with a mild soap and lukewarm water. It severely affects fertility and peri-postnatal development. It is known that orally administered retinoids and their metabolites are secreted in breast milk. Treclin is a medicated gel that contains two different active ingredients, Clindamycin and Tretinoin. For leukemia, it is taken by mouth for up to three months. A pea-sized amount of medication should be squeezed onto one fingertip, dot onto the chin, cheeks, nose, and forehead; then gently rub over the entire face.Treatment with Treclin should not exceed 12 weeks of continuous use without careful evaluation. Patient Info .