Your doctor may occasionally change your dose.
Some of the dosage forms listed on this page may not apply to the brand name Januvia.. For the Consumer. Follow all directions on your prescription label and read all medication guides or instruction sheets. Contact the applicable plan Version: 10.02.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records.
Diseases & Conditions Indicated as adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus who are already treated with sitagliptin or metformin and have inadequate glycemic control on sitagliptin or metformin aloneAdjust dose gradually considering effectiveness and tolerabilityInitial and maintenance dosing should be conservative due to possibility of decreased renal function. /viewarticle/937067 This includes prescription and over-the-counter medicines, Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Januvia only for the indication prescribed.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.Copyright 1996-2020 Cerner Multum, Inc. Many other drugs can also affect blood sugar control. Alcohol, isoniazid, and barbiturates may potentially cause drug interactions with acetaminophen. Controlled studies in pregnant women show no evidence of fetal risk.Sitagliptin: Dipeptidyl peptidase 4 (DPP-4) inhibitor, thereby increasing and prolonging incretin hormone activity which are inactivated by DPP-4 enzyme. 2001 and formulary information changes. Risk factors for metformin-associated lactic acidosis include renal impairment, concomitant use of certain drugs (e.g., carbonic anhydrase inhibitors such as topiramate), age 65 years old or greater, having a radiological study with contrast, surgery and other procedures, hypoxic states (e.g., acute congestive heart failure), excessive alcohol intake, and hepatic impairment
Individual plans may vary Note: This document contains side effect information about sitagliptin. 2002 Ask your doctor about any risks.Januvia is not approved for use by anyone younger than 18 years old.Take Januvia exactly as it was prescribed for you. Be sure your family or close friends know how to give you this injection in an emergency.Januvia is only part of a complete treatment program that may also include diet, exercise, weight control, blood sugar testing, and special medical care.
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Incretins increase insulin release and synthesis from pancreatic beta cells and reduce glucagon secretion pancreatic alpha cellsMetformin: Biguanide; acts by decreasing endogenous hepatic glucose production, decreases intestinal absorption of glucose, and improves insulin sensitivity by increasing peripheral glucose uptake and utilization; improves glucose tolerance and lowers both basal and postprandial plasma glucoseGradually escalate the dose to reduce the gastrointestinal side effects due to metforminExtended-release: Administer once daily, with a meal preferably in the eveningMaintain the same total daily dose of sitagliptin and metformin when changing between immediate-release and extended-release, without exceeding the maximum recommended daily doseAdding plans allows you to compare formulary status to other drugs in the same class.To view formulary information first create a list of plans. It works by regulating the levels of insulin your body produces after eating.. Januvia is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.. Januvia is not for treating type 1 diabetes.. Along with its needed effects, sitagliptin (the active ingredient contained in Januvia) may cause some unwanted effects. Follow your doctor's instructions.Your blood sugar may need to be checked often, and you may need other blood tests at your doctor's office.Your doctor may prescribe a glucagon injection kit in case you have severe hypoglycemia. We comply with the HONcode standard for trustworthy health information - Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature. News These medications are not usually taken together. Medical Societies Advise on Vitamin D in Midst of COVID-19Hyperglycemia Predicts COVID-19 Death Even Without Diabetes Long-term Antibiotic Use Linked to Increased Type 2 Diabetes Risk in WomenManaging Atherosclerotic Cardiovascular Disease in Patients With Type 2 DiabetesShare cases and questions with Physicians on Medscape consult. Call your doctor for medical advice about side effects. Because butalbital can cause drowsiness and a decreased level of consciousness, there is a higher risk of falls, particularly in the elderly, with the potential for subsequent severe injuries. Important Information 2002 Applies to sitagliptin: oral tablet.