Karim A, Ahmed S, Rossoff LJ, Siddiqui RK, Steinberg HN "Possible levofloxacin-induced acute hepatocellular injury in a patient with chronic obstructive lung disease." Pharmacotherapy 22 (2002): 663-8; discussion 668-7249. Lewis JR, Gums JG, Dickensheets DL "Levofloxacin-induced bilateral achilles tendonitis." Int J Clin Pharmacol Ther 50 (2012): 302-635. Clin Infect Dis 46 (2008): 1126-736. Croom KF, Goa KL "Levofloxacin: A Review of its Use in the Treatment of Bacterial Infections in the United States."
BMJ 322 (2001): 46-748. Amankwa K, Krishnan SC, Tisdale JE "Torsades de pointes associated with fluoroquinolones: Importance of concomitant risk factors." Pharmacotherapy 18 (1998): 1255-6316. 2. Kawai T "Clinical evaluation of levofloxacin 200 mg 3 times daily in the treatment of bacterial lower respiratory tract infections." Friedrich LV, Dougherty R "Fatal hypoglycemia associated with levofloxacin."
Infection 28 (2000): 256-752. Kahn JB "Latest industry information on the safety profile of levofloxacin in the US."
In 1 case, a 51-year-old female developed "electrical" sensations, numbness, allodynia, multiple severe tendinitis, partial tendon rupture, impaired memory, confusion, and impaired concentration, with some symptoms persisting after 1 year.-Uncommon (0.1% to 1%): Hyposmia, somnolence, peripheral neuropathy, hearing loss-Very common (10% or more): Fatigue/asthenia (25%), decreased exercise tolerance-Uncommon (0.1% to 1%): Increased blood alkaline phosphatase-Common (1% to 10%): Nausea, vomiting, abdominal pain, diarrhea, constipation-Uncommon (0.1% to 1%): Retching, dyspepsia, flatulence, oral fungal infectionDuring 1 study, C difficile-associated diarrhea occurred in 11 of 490 study patients (2.2%) receiving this drug.Hemorrhagic diarrhea has been reported, which in very rare cases was indicative of enterocolitis (including Attempted or completed suicide reported, especially in patients with medical history of/underlying risk factor for depression.Mucocutaneous reactions have been reported, sometimes after the first dose.A 15-year-old male developed fatal toxic epidermal necrolysis taking this drug for 9 days. N Engl J Med 357 (2007): 206755. Bird SB, Orr PG, Mazzola JL, Brush DE, Boyer EW "Levofloxacin-Related Seizure Activity in a Patient With Alzheimer's Disease: Assessment of Potential Risk Factors." Makaryus AN, Byrns K, Makaryus MN, Natarajan U, Singer C, Goldner B "Effect of ciprofloxacin and levofloxacin on the QT interval: is this a significant "clinical" event?"
Digwood-Lettieri S, Reilly KJ, Haith LR Jr, et al. Zantac (Taladine) Digestive System Treatment: Labetalol Trandate: Antihypertensive Drug Triiodothyronine Thyronamine: Thyroid Hormone: Lidocaine Xylocaine (Zingo) Antiarrhythmic drug and anesthetic: Rifampicin Rifadin IV: Antibiotic: Levothyroxine Thyradin S (Levothroid, Levoxyl) Thyroid Hormone: Levofloxacin Cravit (Levaquin) Antibiotic: Loperamide Lopemin (Diamode, Imodium) …
Infection 37 (2009): 466-823. Seek immediate medical attention if you develop muscle weakness or trouble breathing.Fluoroquinolones, including levofloxacin, are associated with disabling and potentially irreversible serious adverse reactions that have occurred together, including tendinitis and tendon rupture, Along with its needed effects, levofloxacin may cause some unwanted effects. Khaliq Y, Zhanel GG "Fluoroquinolone-Associated Tendinopathy: A Critical Review of the Literature." Pharmacotherapy 21 (2001): 1468-7242. Goodwin SD, Gallis HA, Chow AT, Wong FA, Flor SC, Bartlett JA "Pharmacokinetics and safety of levofloxacin in patients with human immunodeficiency virus infection." Mathis AS, Chan V, Gryszkiewicz M, Adamson RT, Friedman GS "Levofloxacin-Associated Achilles Tendon Rupture." 第一三共株式会社, Daiichi Sankyō Kabushiki kaisha, engl. Corral De La Calle M, Martin Diaz MA, Flores CR, Vidaurrazaga C "Acute localized exanthematous pustulosis secondary to levofloxacin."