et al. RBSilbershatz Amiodarone has a long half-life (40-55 days) for oral chronic therapy. Do not miss any doses. for the GEFCA Investigators–GEMA Group, Buenos Aires, Argentina, Efficacy of amiodarone for the termination of chronic atrial fibrillation and maintenance of normal sinus rhythm. Villani ENChlouverakis Does quality of reports of randomised trials affect estimates of intervention efficacy reported in meta-analyses? PE Intravenous versus oral amiodarone for the conversion of atrial fibrillation of recent onset [abstract]. E Our website uses cookies to enhance your experience. Miller The Digitalis in Acute Atrial Fibrillation (DAAF) Trial Group, Intravenous digoxin in acute atrial fibrillation. Conclusions N Meta-analysis in clinical trials.
G JP GOlshansky Studies that presented insufficient data regarding our primary outcome, conversion to sinus rhythm, for which we could not get additional information from the authors, were also excluded.Our secondary outcomes were mortality and adverse events (AEs), but we did not exclude from the primary analysis studies that failed to report these outcomes.We searched for relevant studies in the electronic databases MEDLINE (January 1966 to February 2001), EMBASE (January 1980 to September 2000), Cochrane Controlled Trial Register (Cochrane Library 2000, issue 3), and Best Evidence (January 1991 to September 2000), using the terms Two of 3 authors (L.M.L., K.U., and J.E.) Chalmers An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Capucci GSchneider The outcome status was available in 1930 patients included in this analysis; 1002 were randomized to amiodarone and 928 to control treatment. Falk
The primary argument against including these studies is that they may be methodologically inferior to published material, and thus are more likely to provide biased results. ALenzi MedicineHow.com does not provide diagnosis or treatment. Fuster GRennie We excluded studies in which 30% or more of the participants had non-AF supraventricular arrhythmias such as atrial flutter and studies that concerned primary prevention of AF.
V Summarizing the evidence. EBMiller TBallester SZaga Five of the 7 authors of abstracts contacted responded to our requests, which allowed us to assess these abstracts using the same standards as for peer-reviewed publications.
Could Viagra, Cialis Help Boost Colon Cancer Survival? Villani It’s … NEpstein Irbesartan oral tablet is a prescription medication used to treat high blood pressure and diabetic nephropathy caused by type 2 diabetes. Quality assessment MFTerracciano JP Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.Mayo Clinic does not endorse companies or products. DGWaldo Roy
ALinnaluoto However, most studies included in our meta-analysis show that amiodarone achieves conversion within 24 hours of administration . Eligibility criteria Amiodarone-induced pulmonary toxicity (APT) is one of the most serious side effects of use. JC Developing optimal search strategies for detecting clinically sound studies in MEDLINE. GOlshansky By using this website you agree to the Terms and Conditions. The Pharmacological Intervention in Atrial Fibrillation (PIAF) trial showed no difference between these 2 strategies in improvement of symptoms and quality of life.Electrical cardioversion and/or antiarrhythmic drugs provide options for clinicians choosing conversion to sinus rhythm. RLBass Wyse Chalmers et al.
NEMarketou et al. Cowan KY Intravenous flecainide versus amiodarone for recent-onset atrial fibrillation.
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Adverse Events Efficacy of agents for pharmacologic conversion of atrial fibrillation and subsequent maintenance of sinus rhythm. Noc
Symptoms include a headache, dizziness, or fainting when standing. The Digitalis in Acute Atrial Fibrillation (DAAF) Trial Group, Intravenous digoxin in acute atrial fibrillation. P Goldschlager MRSegal MMinder MEKaleboubas This raises the possibility of an apparently low RR in the group of studies with short AF duration, even if the drug is highly effective. AKaluski G Long-term efficacy of amiodarone for the maintenance of normal sinus rhythm in patients with refractory atrial fibrillation or flutter. ALDiMarco Benjamin APWard E A Cook Reviewers classified concealment of treatment allocation as adequate if those enrolling patients called a central randomization facility or opened sealed opaque envelopes or if the central pharmacy prepared and distributed numbered drug kits. MDorian