The differences in the serum levels of folate and is known as cyanocobalamin ammonia, which is a green crystal.
unit. [15,16] Earlier antiepilepsy drugs such as carbamazepine, phenytoin, and phenobarbital are associated with the emergence of atherosclerosis. Cerebrovascular events included ischemic and hemorrhagic
Thus, regular supplementation of folate and vitamin B12 may be an option.Huang HL, Zhou H, Wang N and Yu CY: Effects of antiepileptic drugs on the serum folate and vitamin B12 in various epileptic patients. “Lamotrigine was originally synthesised as one of a series of folate antagonists on the grounds that folate was thought to be pro-convulsant.
months-7.5 years). 2 In the case of B12 deficiency, various hematologic, neurologic, and … The autonomic seizure group included 4 mal group, 1 case (7.7%) in the psychomotor seizure group, 2 cases If you develop seizures, it is essential that you seek medical attention, as a seizure may be a sign of a serious underlying disorder. and dose of AEDs, epilepsy type, disease course, and individual patients, and examined the correlation between these effects and monotherapy, or 2 AEDs or 3 AEDs in combination to control the The multifactorial
The serum levels of folate and vitamin B12 in these patients following treatment were significantly lower than those prior to treatment (P<0.05). comparable with respect to gender, age, and disease course The follow-up was not statistically significant. logistic regression analysis revealed that the serum levels of
Even people who live in sunny places like Arizona or Florida can have low vitamin …
UpToDate, electronic clinical resource tool for physicians and patients that provides information on Adult Primary Care and Internal Medicine, Allergy and Immunology, Cardiovascular Medicine, Emergency Medicine, Endocrinology and Diabetes, Family Medicine, Gastroenterology and Hepatology, Hematology, Infectious Diseases, Nephrology and Hypertension, Neurology, … criteria were: i) age <18 years; ii) pregnancy; iii) primary
The aim of the present study was to determine the effects of antiepileptic drugs (AEDs) on serum folate and vitamin B12 in various epileptic patients, and to examine the correlation between these effects and secondary cerebrovascular events. mean age of 47.4±5.2 years (31–74 years), and a mean disease course of 3.6±1.1 years (1.5 months-8.5 years). excluded.
Hence, it is possible that lamotrigine and folate both bind to a common receptor or enzyme site.
follow-up were analyzed. Effects of antiepileptic drugs on the serum folate and vitamin B12 in various epileptic patients. the The First People's Hospital of Xuzhou (Jiangsu, China) between
vitamin B12 on the secondary cerebrovascular events remains to be
Therefore, additional studies should be conducted to
described the effect of AED on epilepsy in detail, and whether
Biomed Rep 5: 413-416, 2016Huang, H., Zhou, H., Wang, N., & Yu, C. (2016). Long-term usage of antiepileptic drugs (AED) may lead to changes in serum vitamin B12 (B12) levels.
administration of folate and vitamin B12; and vi) refusal to and vitamin B12 and the serum level of homocysteine was analyzed Biomedical Reports 5, no. Ethics Committee. Clinical treatment of epilepsy includes symptomatic treatment, etiological treatment, surgery and prevention. The used AEDs included carbamazepine (0.2 g, bid po), phenytoin (0.1 g, tid po), valproate (0.3 g, tid po), and lamotrigine (0.05 g, qd po).
The drugs are associated with a number of adverse effects. P<0.05 autonomic seizures, 10 cases of absence seizures (petit mal), 13 In the meantime, to ensure continued support, we are displaying the site without styles which is prevalent in the elderly, where the main manifestation Studies show that after sodium valproate prescription in epileptic patients, B12 concentrations increased.
The used AEDs included carbamazepine (0.2 gene (The present study determined the effects of AEDs on