There is tentative evidence that its use in pregnancy is safe; however, it is not recommended during breastfeeding. Common side effects include lightheadedness, headache, feeling tired, leg swelling, cough, and shortness of breath. For medical information relating to Covid-19, please consult the Sad. Nifedipine inhibits the transmembrane influx of extracellular calcium ions into myocardial and vascular smooth muscle cells, causing dilatation of the main coronary and systemic arteries and decreasing myocardial contractility. Nifedipine is a dihydropyridine calcium channel blocking agent. Chemical structure of nifedipine. Click to predict properties on the Chemicalize site Nifedipine is a useful anti-anginal agent that also lowers blood pressure. Krym., 55, 2005, 47-54.ass: Semi-standard non-polar; Column diameter: 0.25 mm; Column length: 30 m; Column type: Capillary; Heat rate: 5 K/min; Start T: 70 C; End T: 320 C; End time: 5 min; Start time: 0.5 min; CAS no: 21829254; Active phase: BPX-5; Phase thickness: 0.25 um; Data type: Normal alkane RI; Authors: Song, S.M.
Ann Arbor, MI 48108 Serious side effects may include low blood pressure and heart failure. 1272/2008 1.1 Product Code: 11106 Section 1. Chemical formula: C17H18N2O6 Drugbank ID: DB01115 ATC code(s): C08CA05, C08GA01, C08CA55. Know about technical details of Nifedipine like: chemical name, chemistry structure, formulation, uses, toxicity, action, side effects and more at Pharmacompass.com. Nifedipine, dimethyl ether 1,4-dihydro-2,6-dimethyl-4-(2′-nitrophenyl)-3,5-piridindicarboxylic acid (19.3.16), is synthesized by a Hantsch synthesis from two molecules of a β-dicarbonyl compound—methyl acetoacetate, using as the aldehyde component—2-nitrobenzaldehyde and ammonia.The sequence of the intermediate stages of synthesis has not been completely established [20–23]. Extended release formulations of nifedipine should be taken on an empty stomach, and patients are warned not to consume anything containing A number of persons have developed toxicity due to acute overdosage with nifedipine, either accidentally or intentionally, and via either oral or Nifedipine has additionally been found to act as an Nifedipine (initially BAY a1040) was developed by the The use of nifedipine and related calcium channel antagonists was much reduced in response to 1995 trials that mortality was increased in patients with In India, Nifedipine is manufactured by JB Chemicals, and comes in brands Nicardia Retard ( Nifedipine 10mg, 20mg tablets)O=C(OC)\C1=C(\N/C(=C(/C(=O)OC)C1c2ccccc2[N+]([O-])=O)C)CInChI=1S/C17H18N2O6/c1-9-13(16(20)24-3)15(14(10(2)18-9)17(21)25-4)11-7-5-6-8-12(11)19(22)23/h5-8,15,18H,1-4H33,5-dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylateNifediac package insert, TEVA Pharmaceuticals, Sellersville, Pennsylvania, August, 2009. © Royal Society of Chemistry 2020ass: Standard non-polar; Column diameter: 0.53 mm; Column length: 15 m; Column type: Capillary; Heat rate: 2 K/min; Start T: 240 C; End T: 275 C; End time: 1 min; Start time: 1 min; CAS no: 21829254; Active phase: SPB-1; Phase thickness: 2 um; Data type: Kovats RI; Authors: Wachowiak, R.; Strach, B.; Kopatka, P., Analiza toksykologiczna wybranych pochodnych 1,4-dihydropirydyny w diagnostyce zatruc. Nifedipine was patented in 1967, and approved for use in the United States in 1981. CSID:4330, http://www.chemspider.com/Chemical-Structure.4330.html (accessed 16:41, Sep 16, 2020) ; Marriott, P.; Wynne, P., Comprehensive two-dimensional gas chromatography-quadrupole mass spectrometric analysis of drugs, J. Chromatogr. Med. Nifedipine is used to treat hypertension and chronic stable angina. A, 1058, 2004, 223-232.
Nifedipine. Nifedipine was patented in 1967, and approved for use in the United States in 1981.The approved uses are for the long-term treatment of Nifedipine is also used in high-altitude medicine to treat Finally, nifedipine can be used in the treatment of renal calculi, which are commonly referred to as Nifedipine rapidly lowers blood pressure, and patients are commonly warned they may feel dizzy or faint after taking the first few doses. In the US, Nifedipine (nifedipine systemic) is a member of the drug class calcium channel blocking agents and is used to treat Angina Pectoris Prophylaxis, Heart Failure, High Blood Pressure, Hypertensive Emergency, Hypertrophic Cardiomyopathy, Migraine Prevention, Premature Labor and Raynaud's Syndrome. In It is on the World Health Organization's List of Essential Medicines. US matches: Nifedipine; Nifedipine Capsules Nifedipine is a dihydropyridine calcium channel blocker. The Chemical Identifier fields include common identification numbers, the NFPA diamond U.S. Department of Transportation hazard labels, and a general description of the chemical. The information in CAMEO Chemicals comes from a variety of data sources. Identification of the Substance/Mixture and of the Company/Undertaking Product Name: Nifedipine Company Name: Cayman Chemical Company 1180 E. Ellsworth Rd.
Nifedipine SAFETY DATA SHEET Supersedes Revision: 04/17/2012 according to Regulation (EC) No. Toxicological analysis of selected 1,4-dihydropyridyne calcium channel blockers in the diagnosis of intoxications, Arch. It is available as a generic medication. Click to enlarge. 1907/2006 as amended by (EC) No.