It may harm them. Bicalutamide is 96% bound to plasma proteins.Bicalutamide is stereospecific, with the R-enantiomer producing the active effect, while the S-enantiomer is inactive.
The Possibly. They work in slightly different ways to reduce the action of Testosterone stimulates prostate cancer cells to grow and multiply. Or you might need extra medications to manage your blood sugar levels.If you have diabetes and want to take Casodex, talk with your doctor about the risks and benefits.As with all medications, the cost of Casodex can vary. Below are examples of these side effects.These lists contain examples of more common side effects that can occur with Casodex, with Xtandi, or with both drugs (when taken individually).These lists contain examples of serious side effects that can occur with Casodex, with Xtandi, or with both drugs (when taken individually).Casodex and Xtandi have slightly different FDA-approved uses, but they’re both used to treat metastatic prostate cancer.The use of Casodex and Xtandi in treating metastatic prostate cancer has been directly compared in a Researchers studied men who had castration-resistant metastatic prostate cancer. Food does not affect absorption. Do not crush, split, or chew them. Casodex may not be right for you if you have certain medical conditions or other factors affecting your health. During Casodex/ARIMIDEX treatment the mean growth rate (cm/yr) decreased by 1.6 cm/year, 95% CI (-4.7 to 1.5) p=0.28; the mean growth rate SDS decreased by 0.1 SD, 95% CI (–1.2 to 1.0) p=0.88. They found no significant difference between the two groups.Casodex contains the active drug bicalutamide. It’s a standard treatment option for metastatic prostate cancer, recommended inAfter 160 weeks, 47.3% of the men who took Casodex were still alive, compared with 42.5% of the men who took flutamide.The researchers found that the difference in survival rates between the two groups was not significant. If PSA levels rise during Casodex therapy, the patient should be evaluated for clinical progression. The hazard ratio for time to death (survival) was 0.87 (95% confidence interval 0.72 to 1.05).There was no significant difference in time to objective tumor progression between treatment groups (see Figure 2). The structural and empirical formulas are:Bicalutamide has a molecular weight of 430.37. These drugs lower the amount of testosterone in your body. It slows and sometimes stops the growth and spread of prostate cancer.After oral administration of Casodex, bicalutamide is well absorbed. This Patient Information leaflet summarizes the most important information about Casodex. Don’t stop taking it without talking to your doctor first.Other drugs are available that can treat metastatic Examples of other drugs that may be used to treat metastatic prostate cancer include:You may wonder how Casodex compares to other medications that are prescribed for similar uses. This is prostate cancer for which other medications or surgical treatments that lower testosterone levels are no longer working. For patients who have objective progression of disease together with an elevated PSA, a treatment-free period of antiandrogen, while continuing the LHRH analog, may be considered.Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.In patients with advanced prostate cancer treated with Casodex in combination with an LHRH analog, the most frequent adverse reaction was hot flashes (53%).In the multi-center, double-blind, controlled clinical trial comparing Casodex 50 mg once daily with flutamide 250 mg three times a day, each in combination with an LHRH analog, the following adverse reactions with an incidence of 5% or greater, regardless of causality, have been reported.Other adverse reactions (greater than or equal to 2%, but less than 5%) reported in the Casodex-LHRH analog treatment group are listed below by body system and are in order of decreasing frequency within each body system regardless of causality.Laboratory abnormalities including: elevated AST, ALT, bilirubin, BUN, and creatinine; and decreased hemoglobin and white cell count, have been reported in both Casodex-LHRH analog treated and flutamide-LHRH analog treated patients.The following adverse reactions have been identified during post-approval use of Casodex. Treatment with Casodex should be started at the same time as treatment with an LHRH analog. There is no evidence that bicalutamide induces hepatic enzymes.Casodex is contraindicated for use in pregnant women because it can cause fetal harm.