In general, these medications should not be used together.Corticosteroids, including clobetasol propionate, can make corticorelin less effective. Drug Interactions With Clobetasol Propionate People who are already using aldesleukin or corticorelin may not be able to use clobetasol propionate. If no improvement is seen within 2 weeks, reassessment of the diagnosis may be necessary.Clobetasol Propionate Ointment USP, 0.05% is contraindicated in those patients with a history of hypersensitivity to any of the components of the preparations.Clobetasol Propionate Ointment USP, 0.05% should not be used in the treatment of rosacea or perioral dermatitis, and should not be used on the face, groin, or axillae.Systemic absorption of topical corticosteroids can produce reversible HPA axis suppression with the potential for glucocorticosteroid insufficiency after withdrawal from treatment. Manifestations of intracranial hypertension include bulging fontanelles, headaches, and bilateral papilledema.A limited number of patients at or above 65 years of age have been treated with Clobetasol Propionate Ointment (n = 101) in US and non-US clinical trials. Use in pediatric patients under 12 years of age is not recommended.
Your healthcare professional (such as your doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. It is a white to cream-colored crystalline powder insoluble in water. Interactions.
Apply a thin film of the medication to the affected area and gently rub in, usually 2 times daily or as directed by your doctor. Do not store in the bathroom.
Because many drugs are excreted in human milk, caution should be exercised when Clobetasol Propionate Ointment USP, 0.05% is administered to a nursing woman.Safety and effectiveness of Clobetasol Propionate Ointment USP, 0.05% in pediatric patients has not been established. Occlusive dressing with hydrocortisone for up to 24 hours has not been demonstrated to increase penetration; however, occlusion of hydrocortisone for 96 hours markedly enhances penetration. Clobetasol has no known mild interactions with other drugs.
Pittsburg, PA: GlaxoSmithKline Consumer Healthcare, LP;2002 August.Temovate Scalp Application [package insert]. Some corticosteroids have been shown to be teratogenic after dermal application to laboratory animals.Clobetasol propionate has not been tested for teratogenicity when applied topically; however, it is absorbed percutaneously, and when administered subcutaneously it was a significant teratogen in both the rabbit and mouse.
Clobetasol Propionate Ointment USP, 0.05% contains Clobetasol propionate 0.5 mg/g in a base of propylene glycol, sorbitan sesquioleate, and white petrolatum.
Clobetasol, an analog of prednisolone, has a high degree of glucocorticoid activity and a slight degree of mineralocorticoid activity.Chemically, Clobetasol propionate is (11ß,16ß)-21-chloro-9-fluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)-pregna-1,4-diene-3,20-dione, and it has the following structural formula:Clobetasol Propionate Ointment USP, 0.05% contains Clobetasol propionate 0.5 mg/g in a base of propylene glycol, sorbitan sesquioleate, and white petrolatum.Like other topical corticosteroids, Clobetasol propionate has anti-inflammatory, antipruritic, and vasoconstrictive properties. Avoid freezing.
Keep a list of all your If someone has overdosed and has serious symptoms such as passing out or Laboratory and/or medical tests (such as adrenal gland function tests) may be performed periodically to monitor your progress or check for side effects, especially if you use this drug for an extended period of time or apply it over large areas of the body. Morristown, NJ: Watson Pharma, Inc.;2010 April.Cormax Ointment [package insert]. Pittsburg, PA: GlaxoSmithKline Consumer Healthcare, LP;2002 August.Lexi-Interact [computer program]. This information does not contain all possible interactions or adverse effects. Less frequent adverse reactions were stinging, cracking, erythema, folliculitis, numbness of fingers, skin atrophy, and telangiectasia.Cushing syndrome has been reported in infants and adults as a result of prolonged use of topical Clobetasol propionate formulations.The following additional local adverse reactions have been reported with topical corticosteroids, and they may occur more frequently with the use of occlusive dressings and higher potency corticosteroids. Select one or more newsletters to continue. Summary: Drug interactions are reported among people who take Clobetasol propionate and Synthroid together. Abnormalities seen included cleft palate, cranioschisis, and other skeletal abnormalities.There are no adequate and well-controlled studies of the teratogenic potential of Clobetasol propionate in pregnant women. Fort Worth, TX: Galderma Laboratories;2011 January.Cormax Scalp Application [package insert]. Pittsburg, PA: GlaxoSmithKline Consumer Healthcare, LP;2002 August.Temovate E Emollient Cream [package insert].