Loratadine has no clinically significant sedative or anticholinergic properties in the majority of the population and when used at the recommended dosage.
Ballymacarby, Clonmel, Co. Tipperary, Co. Tipperary, IrelandTo bookmark a medicine you must sign up and log in.To view the changes to a medicine you must sign up and log in. Date of first authorisation/renewal of the authorisationStart typing to retrieve search suggestions. The major metabolite-desloratadine (DL)- is pharmacologically active and responsible for a large part of the clinical effect. Loratadine, like all other antihistamines, may decrease the response to skin prick tests. Axcel Loratadine(loratadine): Symptomatic relief of allergic rhinitis, chronic urticaria & other dermatological disorder.
Usual Adult Dose for Urticaria: 10 mg orally once a day.
Loratadine is not removed by haemodialysis and it is not known if loratadine is removed by peritoneal dialysis.
Safety and efficacy of Loratadine has not been established in children younger than 2 years of age. Loratadine was patented in 1980 and came to market in 1988. Loratadine Syrup: Body Weight >30 kg -- Two 5 ml spoonfuls (10 mg) syrup once daily. When suggestions are available use up and down arrows to review and ENTER to select. Loratadine is an antihistamine medicine that relieves the symptoms of allergies.
The following adverse reactions reported during the post-marketing period are listed in the following table by System Organ Class. Loratadine dosing information.
Use during pregnancy appears to be safe but has not been well studied. Patients with severe liver impairment should be administered a lower initial dose because
It is on the World Health Organization's List of Essential Medicines.
Somnolence, tachycardia, and headache have been reported with overdoses.In the event of overdose, general symptomatic and supportive measures are to be instituted and maintained for as long as necessary. Medical monitoring of the patient is to be continued after emergency treatment.Loratadine, the active ingredient in Loratadine 5mg/5ml Syrup, is a tricyclic antihistamine with selective, peripheral HLoratadine has no clinically significant sedative or anticholinergic properties in the majority of the population and when used at the recommended dosage.
The mean elimination half lives in healthy adult subjects were 8.4 hours (range=3 to 20 hours) for loratadine and 28 hours (range-8.8 to 92 hours for the major active metabolite).Approximately 40% of the dose is excreted in the urine and 42% in the faeces over a 10 day period and mainly in the form of conjugated metabolites.
This information is intended for use by health professionalsBoots Hayfever Relief All Day 5mg/5ml Oral SolutionEach 1 ml of syrup also contains the following excipients:Loratadine 5mg/5ml Syrup is indicated for the symptomatic treatment of allergic rhinitis and chronic idiopathic urticarial in adults and children over the age of 2 years.Body weight more than 30kg: 10ml (10mg) of the syrup once daily;Body weight 30kg or less: 5ml (5mg) of the syrup once daily.Efficacy and safety of Loratadine 5mg/5ml Syrup in children under 2 years of age has not been established.Patients with severe liver impairment should be administered a lower initial dose because they may have reduced clearance of loratadine. This product is provided with a measuring device.
By continuing to browse the site you are agreeing to our policy on the use of cookies. Common side effects include sleepiness, dry mouth, and headache. Less than 1% of the active substance is excreted unchanged in active form, as loratadine or DL.The bioavailability parameters of loratadine and of the active metabolite are dose proportional.The pharmacokinetic profile of loratadine and its metabolites is comparable in healthy adult volunteers and in healthy geriatric volunteers.Concomitant ingestion of food can delay slightly the absorption of loratadine but without influencing the clinical effect.In patients with chronic renal impairment, both the AUC and peak plasma levels (CIn patients with chronic alcoholic liver disease, the AUC and peak plasma levels (CLoratadine and its active metabolite are excreted in the breast milk of lactating women.Preclinical data reveal no special hazard based on conventional studies of safety, pharmacology, repeated dose toxicity, genotoxicity and carcinogenic potential.In reproductive toxicity studies, no teratogenic effects were observed.
However, prolonged parturition and reduced viability of offspring were observed in rats at plasma levels (AUC) 10 times higher than those achieved with clinical doses.This medicinal product does not require any special storage conditions. It is in the second-generation antihistamine family of medication.
Thuốc Axcel Loratadine syrup - Siro, giá Thuốc Axcel Loratadine syrup, Công dụng, chỉ định, liều dùng Axcel Loratadine syrup , Công ty Kotra Pharma (M) Sdn Bhd - MA LAI XI A - Thuocbietduoc.com.vn
Bottle made from Type III Amber Glass with a tamper evident child resistant closure having a polypropylene outer layer and a polyethylene inner layer. Gastric lavage may be considered.