These cause less drowsiness than first-generation antihistamines.No research has concluded that Zyrtec or Claritin is more effective, but some people report better responses with one or the other. Other symptoms, including post-nasal drip, cough, and nasal congestion may also be caused by histamine, This may lead to Claritin building up in the body, which increases the risk of side effects.Everyone reacts to medications differently, but Claritin and Zyrtec may have the following side effects:Some people experience a severe allergic response called Some antihistamines are safe for children, but it is a good idea to talk with a doctor or check the label carefully before giving antihistamines to a child.Claritin and Zyrtec are popular over-the-counter antihistamines. Antihistamines block the action of histamine, and histamine-related symptoms include: A few other negative effects are additionally feasible - such as aching throat, sneezing, headache, light skin rash, fever, pain in the back, stuffy nose, chills, and cough. Neither is clearly better than the other.In this article, we provide detail about the differences between Zyrtec and Claritin. Older antihistamines, called first-generation antihistamines, include: Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. They are less likely to make a person feel drowsy or otherwise affect alertness than older, first-generation antihistamines.The labeling of Zyrtec says that a person should not take it when driving a vehicle or using machinery. NyQuil is an old standby that helps you get the rest your immune system needs to fight off your stuffy nose. These antihistamines have significant side effects termed “anticholinergic” side effects, which may include dry mouth, sleepiness, constipation, and urinary retention. In addition, the other ingredients reduce fever and decrease congestion. The liver has to break down loratadine. At the present time, I feel that Zyrtec is the best antihistamine available in the U.S. for the treatment of allergic rhinitis. Doctors consider them safe and effective treatments for minor allergies.Both are second-generation antihistamines. They are available in various forms, including pills, chewable tablets, and syrups.Regardless of marketing claims, little scientific evidence shows that either is more effective.Zyrtec and Claritin have different active compounds.Zyrtec contains cetirizine hydrochloride, also called cetirizine HCL, while Claritin contains loratadine.Zyrtec and Claritin are second-generation antihistamines. The kidneys break down cetirizine—found in Zyrtec—and the body excretes it in the urine, largely unchanged.Claritin is more likely to interact with other drugs than Zyrtec. Both are second-generation antihistamines, and they generally work the same way in the body.

The body absorbs both antihistamines quickly, but Zyrtec seems to work faster for some people.Researchers are often studying, comparing, and improving antihistamines. If you buy something through a link on this page, we may earn a small commission. At the present time, I feel that Zyrtec is the best antihistamine available in the U.S. for the treatment of allergic rhinitis.
It is my opinion that Zyrtec and Allegra are very closely matched, and very good antihistamines. This is different than impairment, which refers to the concept that someone’s ability to perform various mental and physical tasks is affected. Zyrtec causes sedation five to ten percent more than placebo. Nyquil’s Severe formula contains an antihistamine to relieve itchiness and congestion. Verywell Health uses cookies to provide you with a great user experience.

However, antihistamines are generally less effective at treating post-nasal drip and nasal congestion symptoms, since other chemicals other than histamine may be involved. What Symptoms of Hay Fever Do Antihistamines Treat?
He is an assistant clinical professor at the University of California, San Francisco School of Medicine and currently practices at Central Coast Allergy and Asthma in Salinas, California.