The correct method on how to use it is as follows:If you have any questions about the correct way to use the pessary, please ask your healthcare professional.

Your doctor will tell you how long to use this medication and will monitor your condition with regular check-ups.Vagifem is intended for intravaginal use only.

If prolonged immobilisation is to follow elective surgery, temporarily stopping HRT 4 to 6 weeks earlier is recommended. Please call You are encouraged to report negative side effects of prescription drugs to the FDA. Investigations including appropriate imaging tools, e.g. that long-term use is safe. You can find more information about the Women's Health Initiative substudies, and their results, in the You may have heard of the Women’s Health Initiative (WHI), substudies of which spotlighted some very serious issues By continuing to browse the site you are agreeing to our policy on the use of cookies.
We use cookies to enhance your site experience and for analytics purposes.Like all medications, Vagifem has risks and benefits. Usually the benefits of taking a medication outweigh the associated side effects. • Acute liver disease, or a history of liver disease as long as liver function tests have failed to return to normal

Connect by text or video with a U.S. board-certified doctor now — wait time is less than 1 minute!We are asking our website visitors to consent to the use of cookies by HealthTap to continue to our website. Vagifem works by releasing a hormone called oestradiol, which is a special form of oestrogen. There was one case of complex hyperplasia … The adverse events observed with a higher frequency in patients treated with Vagifem 10 micrograms as compared to placebo and which are possibly related to treatment are presented below.Vaginal haemorrhage, vaginal discharge or vaginal discomfortIn addition to the above mentioned adverse drug reactions, those presented below have been spontaneously reported for patients being treated with Vagifem 25 micrograms and are considered possibly related to treatment. These warnings are most relevent to repeated or long-term use of the vaginal tablets. • Metabolism and nutrition disorders: fluid retention Endometrial safety of Vagifem 10 mcg was additionally evaluated in a second, 12 month, open-label, multicenter safety study. • Leiomyoma (uterine fibroids) or endometriosis Please see the Prescribing Information for more details about who should not use Vagifem ®.You should not use Vagifem … The reporting rate of these spontaneous adverse reactions is very rare (<1/10,000 patient years). There is some evidence from the WHI trial of increased risk of probable dementia in women who start using continuous combined or oestrogen-only HRT after the age of 65.Intravaginal applicator may cause minor local trauma, especially in women with serious vaginal atrophy.Evidence regarding the risks associated with HRT in the treatment of premature menopause is limited. It is a matter of balancing these.
• Known hypersensitivity to the active substances or to any of the excipientsFor the treatment of postmenopausal symptoms, HRT should only be initiated for symptoms that adversely affect quality of life. The AUCThe levels of oestrone and oestrone sulfate seen after 12 weeks of Vagifem 10 micrograms administration did not exceed baseline levels, i.e. In all cases, a careful appraisal of the risks and benefits should be undertaken at least annually, and HRT should only be continued as long as the benefit outweighs the risk.Before initiating or reinstituting hormone therapy, a complete personal and family medical history should be obtained. protein C, protein S, or antithrombin deficiency, see section 4.4) Vagifem is intended for intravaginal use and the dose of estradiol is very low. Benefits include improvement of vaginal health. It allows continued monitoring of the benefit/risk balance of the medicinal product.