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Across both databases and both subcohorts, the proportion of patients with chronic renal disease was highest in the warfarin group (2.9%) and among the patients using DOACs was highest in the apixaban groups (on average 2.2%). 2019 Dec 6;2019(1):194-197. doi: 10.1182/hematology.2019000027.Vedovati MC, Mosconi MG, Isidori F, Agnelli G, Becattini C.J Thromb Thrombolysis. 2019 Feb;47(2):272-279. doi: 10.1007/s11239-018-1785-0.Theusinger OM, Schröder CM, Eismon J, Emmert MY, Seifert B, Spahn DR, Baulig W.Anesth Analg. Similar rates of efficacy and safety outcomes (non–vitamin K antagonist oral anticoagulants versus warfarin) were observed between AF patients with and without cancer. The patient representative in the publication review process expressed appreciation of the real world nature of the study, highlighting the usefulness of such studies for informing doctor-patient discussions.Flow of the included patients for QResearch and Clinical Practice Research Datalink (CPRD) analysisIn the subcohort with atrial fibrillation, across the databases, there were 70 585 (68%) patients taking warfarin, 5537 (5%) taking dabigatran, 16 547 (16%) taking rivaroxaban, and 10 601 (10%) taking apixaban. I would also feel better about traveling with Thai GPO, even if I am just walking in broad daylight through extortionville...err, I mean Thong Lo. I heard 180 baht was the standard recommended retail price written on the pack before but don't know where they sell it for that price or less. Similarly, patients with previous ischaemic strokes were excluded from the analysis of the risk of ischaemic stroke.Three DOACs – dabigatran, rivaroxaban, and apixaban – were compared with warfarin. Values are percentages (numbers) unless stated otherwisePatients without atrial fibrillation: selected baseline characteristics of patients and comorbidities in the QResearch and Clinical Practice Research Datalink (CPRD) cohorts. Only the authors are responsible for analysis, interpretation of the data, and writing the report for publication.Competing interests: All authors have completed the Unified Competing Interest form at Ethical approval: The protocol for QResearch has been published in eprints and was reviewed in accordance with the requirements for the East Midlands Derby Research Ethic Committee (ref 03/4/021).Data sharing: To guarantee the confidentiality of anonymised patient data and health information only the authors have had access to the data during the study in accordance with the relevant licence agreements. Such patients are different in their comorbidities and indications for prescribing, so the risks of ischaemic stroke, venous thromboembolism, and mortality are unlikely to be the same.It is difficult to discern the precise indications for anticoagulation. Patients with missing ethnicity data were included in the white category. In: NICE clinical guideline 92, ed. We also lacked information about over-the-counter purchases of other drugs such as a non-steroidal anti-inflammatory drug or aspirin, but this is likely to have affected only a small number of patients.Between QResearch and CPRD most of the results were consistent, but there were a few differences in rates and hazard ratios.