Author information: (1)Drug Safety Research Unit, Southampton, UK. Wiley Clark DW, Layton D, Wilton LV, Pearce GL, Shakir SA.Drug Saf. endstream Please check for further notifications by email.
The exceptionally low reinfection rate (3 [4%] of 85 participants) in the azithromycin group on day 7 could be the result of a longer suppressive effect resulting from azithromycin's extended tissue-elimination half-life. Randomization and preparation of the study drugs or placebo for administration were done by an author (J.T.)
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doi: 10.1093/omcr/omy111. Norfloxacin is used to treat a variety of bacterial infections.This medication belongs to a class of drugs known as quinolone antibiotics.It works by stopping the growth of bacteria. Rockville, Maryland Selection of norfloxacin- and azithromycin-resistant A stool specimen more likely will yield an NTS-positive culture than will a rectal swab specimen. Our study might slightly underdetect NTS carriage, but the comparability of bacteriological assessment among the 3 treatment groups was maintained.Our study agrees with a previous report by Chiu et al. According to the studies, the rank order of phototoxic potential of fluoroquinolones is as follows: enoxacin> ciprofloxacin > norfloxacin = ofloxacin = levofloxacin = gatifloxacin = moxifloxacin 1, 2. [Reinfection was assumed when an NTS serotype detected in an assessment culture was different from that found in the pretreatment culture. The study also explored the effects of antimicrobial treatment on drug resistance.Each trial participant was given an identification number. Vaginal candidiasis was significantly more frequently associated with the use of the three 4-quinolones than with azithromycin and cefixime but it was frequently delayed until the week or two after the cessation of therapy. Empirical antimicrobial therapy is recommended in selected patient groups: six or more stools per day, with fever and bloody diarrhoea or fever only, symptoms persisting for >1 week, or immunocompromised status. doi: 10.1046/j.1365-2125.1996.03013.x. II. 2. The participants assigned to receive placebo were randomized to receive either norfloxacin placebo or azithromycin placebo, but data for these persons were combined into 1 placebo group for analysis.
Wiley Search for other works by this author on: Within each event, as recorded in these studies, the highest event rates (the number of events per 1000 patients) in the week following the start of therapy were: 9.2 for diarrhoea with cefixime; 4.9 for nausea/vomiting with ofloxacin; 2.4 for rash with azithromycin; 2.2 for abdominal pain with norfloxacin; 1.5 for headache/migraine with ofloxacin; 1.4 for malaise/lassitude with ofloxacin; 1.2 for dizziness with norfloxacin. Lausanne, Other / Non US