Monitor for an exaggerated hypertensive response to dopamine.Droxidopa: Monoamine Oxidase Inhibitors may enhance the hypertensive effect of Droxidopa. 4 CONTRAINDICATIONS . Do not use thioridazine within 5weeks of discontinuing PROZAC.Do not use thioridazine within Specifically, the risk for opioid toxicity (eg, respiratory depression) may be increased.
This could result in serotonin syndrome. This could result in serotonin syndrome. Thrombocytopenia is the most frequently observed blood dyscrasia.• Peripheral and optic neuropathy (with vision loss): Has been reported in adults and children and may occur primarily with extended courses of therapy >28 days; any symptoms of visual change or impairment warrant immediate ophthalmic evaluation and possible discontinuation of therapy. Treatment duration is usually 10 to 14 days (IDSA [Tunkel 2004]; IDSA [Tunkel 2017]; Ntziora 2007; Sipahi 2013).Oral, IV: 600 mg every 12 hours; duration is for ≥7 days and varies based on disease severity and response to therapy.
Use has also been reported in a 10-year old child, treatment was successfully completed with dosing of 600 mg once daily (Condos 2008).Adolescents: 600 mg once daily was reported in a retrospective review of 30 patients (n= four adolescents) and a case report (patient age: 14 years) (Dauby 2011; Schecter 2010). • Myelosuppression: Has been reported and may be dependent on duration of therapy (generally >2 weeks of treatment); use with caution in patients with preexisting myelosuppression, in patients receiving other drugs which may cause bone marrow suppression, or in chronic infection (previous or concurrent antibiotic therapy). This could result in serotonin syndrome. Learn about drug interactions between linezolid oral and lithium carbonate oral and use the RxList drug interaction checker to check drug combinations. HYDROcodone: Monoamine Oxidase Inhibitors may enhance the adverse/toxic effect of HYDROcodone. Management: Discontinue agents that may lower the seizure threshold 48 hours prior to intrathecal use of iohexol. Management: Avoid coadministration of COMT inhibitors and nonselective monoamine oxidase inhibitors (MAOIs) (eg, isocarboxazid, phenelzine, tranylcypromine, linezolid, methylene blue) whenever possible.Cyclobenzaprine: May enhance the serotonergic effect of Monoamine Oxidase Inhibitors. {* license_number *} Several studies indicate that linezolid exposure is increased in patients with significant renal dysfunction (Cattaneo 2016; Gervasoni 2015; Ide 2018; Matsumoto 2010; Nukui 2013; Sasaki 2011; Tsuji 2017) although this may be reduced by a compensatory increase in non-renal elimination (Brier 2003; El-Assal 2014). Available for Android and iOS devices. with linezolid or intravenous methylene blue (4.1) • Pimozide: Do not use.
We comply with the HONcode standard for trustworthy health information - Lactobacillus and Estriol: Antibiotics may diminish the therapeutic effect of Lactobacillus and Estriol. Common side effects of linezolid use (those occurring in more than 1% of people taking linezolid) include diarrhea (reported by 3–11% of clinical trial participants), headache (1–11%), nausea (3–10%), vomiting (1–4%), rash (2%), constipation (2%), altered taste perception (1–2%), and discoloration of … Linezolid is active against most Gram-positive bacteria that cause disease, including streptococci, vancomycin-resistant enterococci (VRE), and methicillin-resistant Staphylococcus aureus (MRSA).