ScienceDaily. "Big data, bench science suggests drug may slow Parkinson's progression in people: Drug used to treat enlarged prostate appears to improve Parkinson's symptoms in experimental models and human database analysis." Parkinson's is a progressive condition affecting the brain, for which there is currently no cure.
Existing data from people with Parkinson’s who have been treated for an enlarged prostate was also used in the study. Prof David Dexter from Parkinson's UK said: "These exciting results show that terazosin may have hidden potential for slowing the progression of Parkinson's, something that is desperately needed to help people live well for longer. "Big data, bench science suggests drug may slow Parkinson's progression in people: Drug used to treat enlarged prostate appears to improve Parkinson's symptoms in experimental models and human database analysis."
Terazosin, a drug for enlarged prostate, might also be able to slow the progression of Parkinson's disease, tests in animal models and analyses of patient data have shown. Parkinson’s disease treatments usually come in the form of physiotherapy and occupational therapy, medication, and in some cases brain surgery. )"The research grew from the discovery by co-senior study author Lei Liu, PhD, at Capital Medical University in Beijing, China, that terazosin, a drug for treating enlarged prostate, or benign prostatic hyperplasia, could also block cell death. "That's a terrible state, because as our population ages Parkinson's disease is going to become increasingly common.Given that terazosin has a proven track record for treating BPH, he says, getting it approved and "repurposed" as a Parkinson's drug should be achievable if the clinical trials go well. "We are currently engaged in planning phase 1 studies that are funded and we are recruiting patients in Iowa.
Have any problems using the site? PARKINSON’S DISEASE is a condition in which parts of the brain become progressively damaged over many years, but currently there’s no cure. Co-researcher Dr Nandakumar Narayanan, who treats patients with Parkinson's disease said: "We need these randomised controlled trials to prove that these drugs really are disease modifying.
These are external links and will open in a new windowA drug used to treat enlarged prostates may be a powerful medicine against Parkinson's disease, according to an international team of scientists. Or view hourly updated newsfeeds in your RSS reader:Keep up to date with the latest news from ScienceDaily via social networks:Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. ScienceDaily, 16 September 2019.
Moreover, the drug could slow or stop neurodegeneration, even if treatment was delayed until after neurodegeneration had started to develop. Age •3.5% of women ages 20 to 29; 33% of women ages 54 –79; 38% of women over 80 (Wu et al., 2014). Patients on the drugs targeting PGK1 appeared to fare better in terms of Parkinson's disease symptoms and progression, which the researchers say warrants more study in Lead researcher Dr Michael Welsh says while it is premature to talk about a cure, the findings have the potential to change the lives of people with Parkinson's. order back issues and use the historic Daily Express This led to increased dopamine levels and improved movement symptoms. But today we have zero treatments that change the progressive course of this neurodegenerative disease. That's a terrible state, because as our population ages Parkinson's disease is going to become increasingly common," says senior study author Michael Welsh, MD, UI professor of internal medicine, a Howard Hughes Medical Institute investigator, and director of the Pappajohn Biomedical Institute at the UI. Tel: 020 7931 8080. So, Welsh turned to Nandakumar Narayanan, MD, PhD, a UI neurologist who cares for patients with PD and studies the disease in people. Fox Foundation for Parkinson's Research. University of Iowa Health Care. Terazosin helps ease benign prostatic hyperplasia (BPH) by relaxing the muscles of the bladder and prostate.But researchers believe it has another beneficial action, on brain cells damaged by Parkinson's.