Adapted from Jenkins TC, Knepper BC, Sabel AL, et al. Dechet AM, Yu PA, Koram N, Painter J. Nonfoodborne Vibrio infections: an important cause of morbidity and mortality in the United States, 1997-2006. Common culprits include aerobic organisms (eg, streptococci, The IDSA recommends parenteral ampicillin-sulbactam or cefoxitin therapy in patients with human-bite wounds, because In general, infections at surgical sites rarely occur in the first 48 hours after surgery, with the exceptions of group A streptococci or clostridial species.Antibiotics and opening the incision are usually required in febrile patients with temperatures above 101.3°F (38.5° C) or tachycardia of 100 beats/min or greater.Procedures that involve nonsterile tissue (eg, intestinal/genital tract, respiratory mucosa) are frequently necessary because of mixed aerobic and anaerobic organism and can involve deeper soft tissues such as fascia and muscle.Skin and soft-tissue infections (SSTIs) in immunocompromised patients can be caused by a variety of organisms, including those that don’t usually produce illness in healthy individuals, or may be the result of an underlying systemic infection.Immunocompromised patients may acquire infections in the hospital, which can present a therapeutic challenge because of the emergence of resistant gram-positive and gram-negative bacteria. Modern Concepts of the Diagnosis and Treatment of Necrotizing Fasciitis. Barrett FF, McGehee RF Jr, Finland M. Methicillin-resistant Staphylococcus aureus at Boston City Hospital. Please confirm that you would like to log out of Medscape.
Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the Infectious Diseases Society of America.
Baxdela (delafloxacin) [package insert]. This image shows cellulitis caused by herpes simplex virus, with the multinucleated organism in the center of the picture.
Chin PW, Koh CK, Wong KT.
Erysipelas of the upper extremity following locoregional therapy for breast cancer. Drugs
Givner LB, Mason EO Jr, Barson WJ, et al. Hematoxylin and eosin (H&E) stain, high power. Non-group A beta-hemolytic streptococcal cellulitis. Zahar JR, Goveia J, Lesprit P, Brun-Buisson C. Severe soft tissue infections of the extremities in patients admitted to an intensive care unit.
Pediatric Dosage Calculator. Seaton RA, Bell E, Gourlay Y, Semple L. Nurse-led management of uncomplicated cellulitis in the community: evaluation of a protocol incorporating intravenous ceftriaxone. Kremer M, Zuckerman R, Avraham Z, Raz R. Long-term antimicrobial therapy in the prevention of recurrent soft-tissue infections.
Decreased antibiotic utilization after implementation of a guideline for inpatient cellulitis and cutaneous abscess. Moran GJ, Krishnadasan A, Gorwitz RJ, Fosheim GE, McDougal LK, Carey RB, et al. Kokx NP, Comstock JA, Facklam RR. Invasive group A streptococcal infections in children with varicella in Southern California. Cieslak TJ, Rajnik M, Roscelli JD. A methodological comparison of prevalence ascertainment. A male patient with orbital cellulitis with proptosis, ophthalmoplegia, and edema and erythema of the eyelids. Cutaneous tuberculosis mimicking cellulitis in an immunosuppressed patient. The margins are irregular but not raised. Four Pediatric Deaths from Community-Acquired Methicillin-Resistant Staphylococcus aureus -- Minnesota and North Dakota, 1997-1999.
Risk factors for clinical failure in patients hospitalized with cellulitis and cutaneous abscess.
Dechet AM, Yu PA, Koram N, Painter J. Nonfoodborne Vibrio infections: an important cause of morbidity and mortality in the United States, 1997-2006. CDC . Bacteriologic and epidemiologic observations.
Decreased Antibiotic Utilization After Implementation of a Guideline for Inpatient Cellulitis and Cutaneous Abscess.
The initial outpatient-physician encounter in group A streptococcal necrotizing fasciitis.
Kroshinsky D, Grossman ME, Fox LP.
Waldhausen JH, Holterman MJ, Sawin RS. Baxdela (delafloxacin) [package insert]. Instead of the presence of yellow fat, the tissue is hemorrhagic and necrotic.
Vugia DJ, Peterson CL, Meyers HB, et al.