Hepatic impairment: 75 mg/day. Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature. Select one or more newsletters to continue.
Conversely, at least 14 days should be allowed after stopping WELLBUTRIN before starting an MAOI antidepressant Do not start WELLBUTRIN in a patient who is being treated with a reversible MAOI such as linezolid or intravenous methylene blue. Diseases & Conditions Contact the applicable plan The following information includes only the average doses of this medicine. Dosing Modifications Hepatic impairment. After 4 days of dosing, the dose may be increased to the target dose of 300 mg once daily in the morning. This website also contains material copyrighted by 3rd parties. Follow your doctor's orders or the directions on the label. wellbutrin-zyban-bupropion-342954 https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9yZWZlcmVuY2UubWVkc2NhcGUuY29tL2RydWcvd2VsbGJ1dHJpbi16eWJhbi1idXByb3Bpb24tMzQyOTU0
WELLBUTRIN SR tablets should be swallowed whole and not crushed, divided, or chewed. Drug interactions can increase the risk of hypertensive reactions. WELLBUTRIN SR may be taken with or without food. Titrate to 150-450 mg/day based on tolerability and efficacy; may administer in divided doses or in ER or SR formulations. Wellbutrin (bupropion hydrochloride) is indicated for the treatment of major depressive disorder(MDD), as defined by the Diagnostic and Statistical Manual (DSM). In patients with mild hepatic impairment (Child-Pugh score: 5 to 6), consider reducing the dose and/or frequency of dosing Consider reducing the dose and/or frequency of WELLBUTRIN in patients with renal impairment (Glomerular Filtration Rate less than 90 mL per min) At least 14 days should elapse between discontinuation of an MAOI intended to treat depression and initiation of therapy with WELLBUTRIN. The recommended starting dose for SAD is 150 mg once daily. In a patient who requires more urgent treatment of a psychiatric condition, non-pharmacological interventions, including hospitalization, should be considered In some cases, a patient already receiving therapy with WELLBUTRIN may require urgent treatment with linezolid or intravenous methylene blue. The dose of this medicine will be different for different patients. Individual plans may vary It is unknown whether the dose of WELLBUTRIN needed for maintenance treatment is identical to the dose that provided an initial response.
and formulary information changes. In a small, 8-week open-label trial (n = 8), adolescents with major depression were given a mean dose of 362 mg/day PO of bupropion SR after titration; this regimen was effective as assessed by the expanded Hamilton Depression Rating Scale (SIGH-SAD).
2002 Initiate dosing with 150 mg per day given as a single daily dose in the morning.
Periodically reassess the need for maintenance treatment and the appropriate dose for such treatment.In patients with moderate to severe hepatic impairment (Child-Pugh score: 7 to 15), the maximum dose of WELLBUTRIN is 75 mg per day. After 3 days of dosing, the dose may be increased to the 300-mg-per-day target dose, given as … To minimize the risk of seizure, increase the dose gradually [see Warnings and Precautions (5.3)]. Aplenzin, Buproban, Wellbutrin SR, Wellbutrin XL, Forfivo XLencoded search term (bupropion (Wellbutrin XL%2C Zyban)) and bupropion (Wellbutrin XL, Zyban) New Data on Birth Defects With Antidepressant Use in PregnancyCan E-Cigarettes and Pharmaceutical Aids Increase Smoking Cessation and Reduce Cigarette Consumption?FDA Questions Validity of Smoking Cessation Drug ResearchFive Healthy Lifestyle Choices Tied to Dramatic Cut in Dementia RiskNew Data on Birth Defects With Antidepressant Use in PregnancySupplement Plus Probiotic May Improve Depressive Symptoms COVID-19 Tied to Wide Range of Neuropsychiatric ComplicationsNew Data on Birth Defects With Antidepressant Use in PregnancyShare cases and questions with Physicians on Medscape consult. Available for Android and iOS devices.
150.