Read the Medication Guide provided by your pharmacist before you start taking diclofenac and each time you get a refill. Supportive measures should be given for complications such as hypotension, renal failure, gastrointestinal disorder, and respiratory depression.Other measures may be indicated by the patient's clinical condition.Diclofenac Potassium tablets contain the potassium salt of diclofenac, a non-steroidal compound with pronounced and clinically demonstrable analgesic, anti-inflammatory and anti-pyretic properties. hypertension, hyperlipidaemia, diabetes mellitus, smoking) should only be treated with diclofenac after careful consideration. In particular it is recommended that the lowest effective dosage be used in frail elderly patients or those with a low body weight (see also precautions) and the patient should be monitored for GI bleeding during NSAID therapy.Diclofenac is contraindicated in patients with established congestive heart failure (NYHA II-IV), ischemic heart disease, peripheral arterial disease and/or cerebrovascular disease (see section 4.3 Contraindications).Patients with congestive heart failure (NYHA-I) or significant risk factors for cardiovascular disease should be treated with diclofenac only after careful consideration. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects. Hepatitis may occur with diclofenac without prodromal symptoms. When suggestions are available use up and down arrows to review and ENTER to select. • Hypersensitivity to the active substance or any of the excipients.
The age of the patient has no influence on the absorption, metabolism, or excretion of diclofenac.
During prolonged treatment with Diclofenac, regular monitoring of hepatic function is indicated as a precautionary measure.If abnormal liver function tests persist or worsen, clinical signs or symptoms consistent with liver disease develop or if other manifestations occur (eosinophilia, rash), diclofenac should be discontinued. * The frequency reflects data from long-term treatment with a high dose (150 mg/day).Clinical trial and epidemiological data consistently point towards an increased risk of arterial thrombotic events (for example myocardial infarction or stroke) associated with the use of diclofenac, particularly at high doses (150mg daily) and in long term treatment. Patients should remain alert for the signs and symptoms of serious arteriothrombotic events (e.g. The remainder of the dose is eliminated as metabolites through the bile in the faeces. Because different brands deliver different amounts of medication, do not switch brands of diclofenac without your doctor's permission and directions.The dosage is based on your medical condition, response to treatment, and other If you are taking this drug on an "as needed" basis (not on a regular schedule), remember that pain medications work best if they are used as the first Tell your doctor right away if any of these unlikely but serious side effects occur: hearing changes (such as Get medical help right away if any of these rare but very serious side effects occur: signs of This drug may rarely cause serious (possibly fatal) This is not a complete list of possible side effects. Patients should be instructed to see a physician immediately in case of such an event.Use of diclofenac are recommended only for short term treatment.During prolonged treatment with diclofenac, as with other NSAIDs, monitoring of the blood count is recommended. Approx.
As fluid retention and oedema have been reported in association with NSAIDs therapy, including diclofenac, particular caution is called for in patients with impaired cardiac or renal function, history of hypertension, the elderly, patients receiving concomitant treatment with diuretics or medicinal products that can significantly impact renal function, and those patients with substantial extracellular volume depletion from any cause, e.g. This site uses cookies. Repeated oral administration of Diclofenac Potassium tablets for 8 days in daily doses of 50 mg t.d.s does not lead to accumulation of diclofenac in the plasma. Patients appear to be at the highest risk of these reactions early in the course of therapy: the onset of the reaction occurring in the majority of cases within the first month of treatment. Dewasa: dosis awal 50 mg pada serangan pertama. Dewasa: 50 mg, 3 kali sehari. Diclofenac may reversibly inhibit platelet aggregation (see anticoagulants in section 4.5 Interaction with other medicaments and other forms of interactions). Caution is called for when using diclofenac in patients with hepatic porphyria, since it may trigger an attack.