Please consult the latest official manual style if you have any questions regarding the format accuracy.Therapeutic: anticonvulsants, antiglaucoma agents, diuretics, ocular hypotensive agentsLowering of intraocular pressure in the treatment of glaucoma. 0000024966 00000 n Cosopt (dorzolamide hydrochloride-timolol maleate) is a combination of a carbonic anhydrase inhibitor and a beta-blocker that reduces pressure in the eye and is used to treat certain types of glaucoma and other causes of high pressure inside the eye. Fundoscopy showed extensive bilateral choroidal detachment. Call your doctor for medical trailer 0000002227 00000 n Alkaline diuresis prevents precipitation of uric acid or cystine in the urinary tract. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. taken, how much, and when it happened. You may need to read it again. Dorzolamide is available as a combination eye drop with a beta-blocker called timolol, in a brand called Cosopt®. Otherwise it is hidden from view. Dorzolamide and Timolol ophthalmic solution, Bausch Health, 22.3 mg-6.8 mg/mL, 10 mL bottle, 1 count, NDC 24208-0486-10 Estimated Resupply Dates Sandoz has dorzolamide/timolol 2%/0.5% ophthalmic solution in 10 mL bottles on back order and the company cannot estimate a release date. Canadian drug name. Dorzolamide ((4S,6S)-4-(ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide) has two pKa values (i.e., 6.4 and 8.5).5,6-Dihydro-(S)-4-(ethylamino)-(S)-6-methyl-4H-thieno(2,3-b)thiopyran-2-sulfonamide7,7-dioxide; For the most part, the safety profile of dorzolamide in children is analogous to that in adults.
0000035096 00000 n Serious side effects include Steven Johnson syndrome.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, - If you have any further questions, ask your doctor or pharmacist. Monitor signs of hypersensitivity reactions and anaphylaxis, including pulmonary symptoms (tightness in the throat and chest, wheezing, cough, dyspnea) or skin reactions (rash, pruritus, urticaria).

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Inhibition of renal carbonic anhydrase, resulting in self-limiting urinary excretion of sodium, potassium, bicarbonate, and water. This could have been influenced by dorzolamide.An 80-year-old Caucasian woman developed eruptions on her arms, lips and ears, with peri-ocular and peri-oral hyperemia after taking timolol + dorzolamide (CosoptErythema multiforme can rarely occur with topical sulfonamide derivatives, in particular dorzolamide. All anti-glaucoma medications were withdrawn and within 2 months the choroidal detachment resolved.Achieving very low intraocular pressures with any combination of anti-glaucoma medications can result in choroidal detachment, which may be heralded by sudden reduction in visual acuity.In a series of patient-blinded experiments with challenges and re-challenges with dorzolamide and latanoprost, the dysosmia only occurred with dorzolamide. Dorzolamide hydrochloride is described chemically as: (4. Genetic Implication.

Those allergic to sulfonamides may be allergic to dorzolami < This div only appears when the trigger link is hovered over. If you have any questions regarding the information, consult your doctor or pharmacist. Dorzolamide/Timolol eye drops solution is comprised of two components: dorzolamide hydrochloride and timolol maleate.
xref Read the Patient Information Leaflet provided by your pharmacist before you start using timolol/dorzolamide and each time you get a refill. CAPITALS indicate life-threatening, underlines indicate most frequent. Report these signs immediately to the physician.Monitor any changes in vision to help document drug effectiveness in decreasing glaucoma.If used as an anticonvulsant, document the number, duration, and severity of seizures to help determine if this drug is effective in reducing seizure activity.Assess signs of parasthesia (numbness, tingling) or muscle twitching. 0000006975 00000 n Dorzolamide 20 mg/ml Eye Drops, Solution (Dorzolamide hydrochloride) Read all of this leaflet carefully before you start using this medicine because it contains important information for you. NDA 20-869/S-034 Page 3 COSOPT® (dorzolamide hydrochloride-timolol maleate ophthalmic solution) Sterile Ophthalmic Solution . Topics beginning with were found in Davis’s Drug Guide.