Consider appropriate washout times when switching from corticosteroid use or from one NSAID to another in dogs. x�b```b``�e`e`�/d`@ �+� �����9�9�KFS��L��2�300�ffZ8{�vˉM� �efy!ui���L��^-ϷL9���)&Qs�A+�-+[��j ��v�Dd����_u2�O�A�B��9�Z>˸BT�J��]^Pز�h�f�t oc�5LJi@�1���(�д ͖�$hl�� bBJ` ��J!��0(7�/��r�O���K��We`�f�a�e� �=d��p���O3hr�a�`8�����Ƞ�����n�B�d�H1�10��< �:N� �*�U�c�=Q�,M�J�o��3�ɲ��b�c`�jB@� *�fs
It is soluble in water, methanol, and chloroform. As a class, cyclo-oxygenase inhibitory NSAIDs may be associated with gastrointestinal, renal and hepatic toxicity.
Meloxicam is not recommended for use in dogs with bleeding disorders, as safety has not been established in dogs with these disorders. 0000010267 00000 n The structural formula is:The molecular formula is C22H26N2O4S•HClDiltiazem hydrochloride is a white to off-white crystalline powder with a bitter taste. Diltiazem hydrochloride is a white to off-white crystalline powder with a bitter taste. Updated: 2020-09-02The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. 0000003673 00000 n Package Insert for Cats NADA 141-219, Approved by FDA Metacam® (meloxicam) 5 mg/mL Solution for Injection Non-steroidal anti-inflammatory drug for use in dogs and cats only Caution: Federal law restricts this drug to use by or on the order of a licensed veterinarian. 399 0 obj <> endobj startxref 0000008579 00000 n Based upon intravenous administration in Beagle dogs, the meloxicam volume of distribution in dogs (Vdλ) is approximately 0.32 L/kg and the total systemic clearance is 0.01 L/hr/kg.
For dogs between 1 - 10 pounds, Metacam Oral Suspension can be given by drops or by using the measuring syringe provided in the package (see dosing procedure below). The use of concomitantly protein-bound drugs with Metacam 5 mg/mL Solution for Injection has not been studied in dogs. trailer 0000004721 00000 n 0000052821 00000 n Drug compatibility should be monitored in patients requiring adjunctive therapy. 0000004964 00000 n The influence of concomitant drugs that may inhibit metabolism of Metacam 5 mg/mL Solution for Injection has not been evaluated. 0000055492 00000 n 0000001702 00000 n 0000000796 00000 n The effect of cyclo-oxygenase inhibition and the potential for thromboembolic occurrence or a hypercoagulable state has not been studied.In foreign suspected adverse drug reaction (SADR) reporting, adverse reactions related to meloxicam administration included: auto-immune hemolytic anemia (1 dog), thrombocytopenia (1 dog), polyarthritis (1 dog), nursing puppy lethargy (1 dog), and pyoderma (1 dog).The following adverse reactions are based on post-approval adverse drug event reporting.
Warning: Repeated use of meloxicam in cats has 0000004174 00000 n Renal changes ranged from dilated medullary and cortical tubules and inflammation of the interstitium, to necrosis of the tip of the papilla in 2 of 6 dogs in the 1X group, 2 of 6 dogs in the 3X group, and 4 of 6 dogs in the 5X group.Copyright © 2020 Animalytix LLC. Metacam ® (meloxicam) 1.5 mg/mL Oral Suspension (equivalent to 0.05 mg per drop) ... be given using the measuring syringe provided in the package (see dosing procedure below). Use the lowest effective dose for the shortest duration consistent with individual response.Dogs with known hypersensitivity to meloxicam should not receive Metacam 5 mg/mL Solution for Injection.The safe use of Metacam 5 mg/mL Solution for Injection in dogs younger than 6 months of age, dogs used for breeding, or in pregnant or lactating bitches has not been evaluated.
0000009637 00000 n H�l��n�0��x[���4 #���!�6�j�ލ=DH�A@���/��Ъ����ΐ?���T�k���'U71 %%EOF However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert.We comply with the HONcode standard for trustworthy health information - 0000003374 00000 n Patients at greatest risk for renal toxicity are those that are dehydrated, on concomitant diuretic therapy, or those with existing renal, cardiovascular, and/or hepatic dysfunction. Diltiazem hydrochloride injection is a clear, colorless, sterile, nonpyrogenic solution. Dogs that have experienced adverse reactions from one NSAID may experience adverse reactions from another NSAID. 0000001350 00000 n 0000005538 00000 n