Amphotericin B is an antifungal medication that fights infections caused by fungus.Amphotericin B is used to treat serious, life-threatening fungal infections. The concentrate (5 mg Amphotericin B per mL after reconstitution with 10 mL Sterile Water for Injection USP) may be stored in the dark, at room temperature for 24 hours, or at refrigerator temperatures for one week with minimal loss of potency and clarity. It is not for use in treating a minor fungal infection (yeast infection) of the mouth, esophagus, or vagina.Do not use amphotericin B in larger amounts than recommended. Amphotericin B binds to ergosterol, an essential component of the fungal cell membrane, thereby causing depolarization of the membrane and altering cell membrane permeability.This leads to leakage of important intracellular components, cell rupture, and eventually cell death. Ask your doctor or pharmacist for more information.Tell your doctor if you have any side effect that bothers you or that does not go away.Call your doctor for medical advice about side effects. It is administered either topically or orally and is often used as a first-line agent for treating onychomycosis, a fungal nail infection. We comply with the HONcode standard for trustworthy health information -
Microglia are strongly linked to ful substances also bleeding, threatened abortion or create a healthy weight. Verify the product name and dosage pre-administration, especially if dose exceeds 1.5 mg/kg. Produit meme effet que le viagra; Generic cialis tadalafil 20 mg india; Purchase cialis daily; Order viagra online canada for reviews for viagra professional J endourol. Select one or more newsletters to continue. Amphotericin B will not treat a Call your doctor for instructions if you miss an appointment for your amphotericin B injection.Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Literature reports have suggested that total body irradiation may be a predisposition.Whenever medication is interrupted for a period longer than seven days, therapy should be resumed by starting with the lowest dosage level, e.g., 0.25 mg/kg of body weight, and increased gradually as outlined under Renal function should be monitored frequently during Amphotericin B therapy (see It is also advisable to monitor on a regular basis liver function, serum electrolytes (particularly magnesium and potassium), blood counts, and hemoglobin concentrations.
This potent drug should not be used to treat noninvasive fungal infections, such as oral thrush, vaginal candidiasis and esophageal candidiasis in patients with normal neutrophil counts.Amphotericin B for Injection USP is specifically intended to treat potentially life-threatening fungal infections: aspergillosis, cryptococcosis (torulosis), North American blastomycosis, systemic candidiasis, coccidioido-mycosis, histoplasmosis, zygomycosis including mucormycosis due to susceptible species of the genera Amphotericin B may be useful in the treatment of American mucocutaneous leishmaniasis, but it is not the drug of choice as primary therapy.This product is contraindicated in those patients who have shown hypersensitivity to Amphotericin B or any other component in the formulation unless, in the opinion of the physician, the condition requiring treatment is life-threatening and amenable only to Amphotericin B therapy.Amphotericin B is frequently the only effective treatment available for potentially life-threatening fungal disease. In animal studies, pregnant animals were given amphotericin B and some babies had problems. See the “Amphotericin B Precautions” section.Common side effects of amphotericin B include the following:This is not a complete list of amphotericin B side effects.
Mammalian cell membranes also contain sterols and it has been suggested that the damage to human cells and fungal cells may share common mechanisms.An initial intravenous infusion of 1 to 5 mg of Amphotericin B per day, gradually increased to 0.4 to 0.6 mg/kg daily, produces peak plasma concentrations ranging from approximately 0.5 to 2 mcg/mL. 8. You may report side effects to the FDA at 1-800-FDA-1088.Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.
An overdose can cause death.You should not receive this medicine if you are allergic to any formulation of amphotericin B (Abelcet, To make sure amphotericin B is safe for you, tell your doctor if you have:an electrolyte imbalance (such as low levels of potassium or magnesium in your blood);Amphotericin B is not expected to harm an unborn baby.
Anyssa Garza received her Doctor of Pharmacy degree from the University of Texas at Austin. Copyright © 2000 - 2020 Jobson Medical Information LLC unless otherwise noted. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. Version: 2.03.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records.