The drug should be used with caution in patients with diminished pulmonary function, and is contraindicated in patients with asthma or a history of asthma and in patients with severe chronic obstructive pulmonary disease. Care should be taken to avoid contamination of the solution container. Applies to timolol ophthalmic: ophthalmic gel forming solution, ophthalmic solution. Timolol ophthalmic solution is contraindicated in patients with bronchial asthma or a history of bronchial asthma and in patients with severe chronic obstructive pulmonary disease, sinus bradycardia, atrioventricular block greater than first degree, overt cardiac failure, or cardiogenic shock. Side effects requiring immediate medical attention. You can submit for FSA reimbursement in two ways: Oral timolol dosages of 1 g/kg daily (142,000 times the systemic exposure following the maximum recommended human ophthalmic dosage) were maternotoxic and resulted in an increased number of fetal resorptions in mice. If timolol is used to reduce IOP in patients with angle-closure glaucoma, the drug should not be used alone but rather in combination with a topical miotic since timolol has little or no effect on pupil size.Like levobunolol, timolol reduces elevated IOP in patients with chronic open-angle glaucoma without producing the miosis and/or ciliary spasm that are associated with miotic agents. When used in conjunction with these agents, timolol may have an additive IOP-lowering effect. Flexible Spending Accounts will reimburse you for incurred expenses during your FSA plan year (period of coverage).
Timoptic (timolol ophthalmic)."
Dosages exceeding 1 drop of a 0.5% solution twice daily generally have not produced a further reduction in IOP.
Timolol Maleate Drops Side Effects by Likelihood and Severity INFREQUENT side effects.
Its chemical name is (-)-1-(tert-butylamino)-3[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]-2-propanol maleate (1:1) (salt). This interaction has been attributed to inhibition of timolol metabolism (via the cytochrome P-450 [CYP] 2D6 isoenzyme) by quinidine. Patients receiving ophthalmic gel-forming solutions of the drug who also are receiving other ophthalmic preparations should be instructed that other topical preparations be administered at least 10 minutes before a dose of the gel-forming solution.Dosage of timolol maleate or timolol (as the hemihydrate) is expressed in terms of timolol.When used alone or when added to existing glaucoma therapy, the usual initial dosage of timolol is 1 drop of a 0.25% solution in the affected eye(s) twice daily. Sunshine Health Florida Medicaid & Health Insurance Website Alopecia, psoriasiform rash, exacerbation of psoriasis, and systemic lupus erythematosus also have been reported.Diarrhea, nausea, dyspepsia, anorexia, and dry mouth have been reported in patients receiving topical timolol therapy.Retroperitoneal fibrosis, impotence, decreased libido, and Peyronie's disease have been reported in some patients receiving topical timolol therapy.Because β-adrenergic blocking agents may mask the signs and symptoms of acute hypoglycemia, these agents should be administered with caution in patients subject to spontaneous hypoglycemia and in diabetic patients (especially those with labile diabetes) who are receiving insulin or oral hypoglycemic agents.
Because of the potential for serious adverse reactions from timolol in nursing infants, a decision should be made whether to discontinue nursing or the drug, taking into account the importance of the drug to the woman.When used in conjunction with topical miotics, latanoprost, and/or topical or systemically administered carbonic anhydrase inhibitors, the effect of timolol in lowering IOP may be additive. Patients suspected of developing thyrotoxicosis should be managed carefully to avoid abrupt withdrawal of β-adrenergic blocking agents that might precipitate a thyroid storm.Common cold and pain in the extremities have been reported in some patients receiving topical timolol therapy.
Patients should be informed that improper handling of ocular solutions can result in contamination of the solution by common bacteria known to cause ocular infections and should be instructed to avoid allowing the tip of the dispensing container to contact the eye or surrounding structures. In ophthalmology, topical timolol is used to reduce elevated IOP in patients with open-angle glaucoma or ocular hypertension. Timolol Maleate Ophthalmic Gel Forming Solution is a non-selective beta-adrenergic receptor blocking agent. Your FSA Administrator might provide you with an FSA Debit Card to use toward FSA eligible expenses. Although not all of these side effects may occur, if they do occur they may need medical attention.