Use the medicine at least 15 minutes before inserting your contact lenses.Turn the bottle upside down and shake it once just before each use.To apply the AzaSite eye drops: Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Know the medicines you take. Its chemical name is (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribohexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]1-oxa-6-aza-cyclopentadecan-15-one, and the structural formula is: It may harm them. In patients receiving systemically administered azithromycin, serious allergic reactions, including angioedema, anaphylaxis, and dermatologic reactions including Stevens-Johnson syndrome and toxic epidermal necrolysis have been reported rarely in patients on azithromycin therapy.
These opinions do not represent the opinions of WebMD. Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in one clinical trial of a drug cannot be directly compared with the rates in the clinical trials of the same or another drug and may not reflect the rates observed in practice.
Your symptoms may improve before the infection is completely cleared.Stop using AzaSite and get emergency medical help if you have any Do not use this medication while wearing contact lenses.
This reaction occurred in approximately 1-2% of patients. In the animal studies, no evidence of harm to the fetus due to azithromycin was found. These doses are estimated to be approximately 5,000 times the maximum human ocular daily dose of 2 mg.
It is not known if AzaSite is safe and effective in children less than 1 year of age. Your symptoms may improve before the infection is completely cleared. NDC 17478-307-04: 2.5 mL in 4 mL bottle containing a total of 25 mg of azithromycin in a white, round, low-density polyethylene (LDPE) bottle, with a clear LDPE dropper tip, and a tan colored high density polyethylene (HDPE) eyedropper cap. In a randomized, vehicle-controlled, double-blind, multicenter clinical study in which patients were dosed twice daily for the first two days, then once daily on days 3, 4, and 5, AzaSite solution was superior to vehicle on days 6-7 in patients who had a confirmed clinical diagnosis of bacterial conjunctivitis. The efficacy of AzaSite in treating bacterial conjunctivitis in pediatric patients one year or older has been demonstrated in controlled clinical trials [see Clinical Studies (14)].No overall differences in safety or effectiveness have been observed between elderly and younger patients.Store unopened bottle under refrigeration at 2° to 8 °C (36° to 46°F).Once the bottle is opened, store at 2° to 25° C (36 ° to 77°F) for up to 14 days. Do not freeze.After opening the bottle, store at room temperature for up to 14 days. User-generated content areas are not reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions. found this review helpful.Questions about medications?
The microbiological success rate for the eradication of the baseline pathogens was approximately 88% compared to 66% of patients treated with vehicle (p<0.001, confidence interval around the 22% difference was 13% to 31%). Version: 4.01.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Whenever clinical judgment dictates, the patient should be examined with the aid of magnification, such as slit-lamp biomicroscopy, and where appropriate, fluorescein staining.
Based on the proposed dose of one drop to each eye (total dose of 100 mcL or 1 mg) and exposure information from systemic administration, the systemic concentration of azithromycin following ocular administration is estimated to be below quantifiable limits (≤10 ng/mL) at steady-state in humans, assuming 100% systemic availability.