The dog has no previous history of disease and was completely normal 72 hours prior to initial presentation. Dodds Video, 2016 Minimal and Non Core Vaccinations, Kennel Cough, Leptospirosis, Lyme, Influenza.Blood Bank, Consultation Form, Test Forms, Information on Hypothyroidism and Clotting disorders.Azathioprine (brand name Imuran or Imurel) is an immuno-suppressant drug used for the treatment of auto-immune conditions such as Azathioprine should be given WITH FOOD, 2 hours before or 2 hours after stomach protectors, which can stop proper absorption of the drug.Dose is usually 1 mg/lb/day for 7-10 days , then taper down over several weeks. Your veterinarian will advise you on a dosing schedule that will taper the drug's dose over several months.If a dose is missed, give it as soon as you can. The immune system normally defends the body from bacteria …
Do not give two doses at the same time.Store in a tight, light resistant, childproof container in a cool, dry place at room temperature away from heat and direct sunlight.Reconstituted injection should be used within 24 hours.Keep this and all medication out of reach of children and pets.Wear gloves while handling this medication as it can cause side effects in humans. Visit a veterinary If it is time already for the next dose, skip the missed dose and go back to the normal schedule. Interactions with other drugs include allopurinol, ACE inhibitors, (e.g. Azathioprine led to increases in liver‐derived serum transaminases and focal hepatic necrosis in dogs dosed experimentally with 1–4 mg/kg/day for 1–6 months.12, 13 In our study, dosage was not a detectable risk factor for hepatotoxicosis, but the number of affected dogs was small. In the long term, Azathioprine may only be required every other day or even less often.Azathioprine has serious & extreme interactions with some other drugs & moderate/mild interactions with others.
It is sometimes used with caution in cats. Thankfully she is doing well now and starting to cut down on the pred. Dogs: Azathioprine is approved to use as an immunosuppressive to treat immune mediated diseases, such as immune mediated hemolytic anemia, certain types of kidney disease, autoimmune skin diseases, lupus, and rheumatoid arthritis.
Also known as Imuran®, is used to treat a number of autoimmune diseases in dogs.
In the second, a case series of dogs with IMHA and severe thrombocytopenia, dogs that received azathioprine (in combination with other drugs) were 4.27 times more likely to survive to 30 days after initiation of treatment compared to dogs that did not receive the drug, although the authors speculated that administration was more likely to have been a marker of survival (because dogs … With long-term use, there are increased risks for neoplasms. 12, 13 In our study, dosage was not a detectable risk factor for hepatotoxicosis, but the number of affected dogs was small. Presented to the primary care veterinarian the next day for lethargy.
ALL PROFITS DONATED TO ANIMAL SHELTERS AND RESCUES SELECTED BY OUR CUSTOMERS! Immune-mediated hemolytic anemia can be fatal if not treated. If your veterinarian does prescribe this drug for your cat, follow the dosing instructions very carefully. Azathioprine must NEVER be given to animals being used for breeding as it can alter DNA transcription in fast growth cells. It should be given only for the condition for which it was prescribed. Azathioprine led to increases in liver‐derived serum transaminases and focal hepatic necrosis in dogs dosed experimentally with 1–4 mg/kg/day for 1–6 months.
Careful weaning to reduce the dosage is advisable when the dog has reached a stable condition.OpenStax College. Immune-mediated hemolytic anemia in dogs is a disease where the immune system attacks and breaks down the body’s red blood cells. It is often used in conjunction with other drugs. ALL PROFITS DONATED TO ANIMAL SHELTERS AND RESCUES SELECTED BY OUR CUSTOMERS!